SSN3/YPL042C Literature Guide Help

Other names published for SSN3: GIG2, NUT7, SRB10, UME5, RYE5, CDK8, YPL042C

SSN3 - Genetic Interactions (35)

ReferenceOther Genes Addressed
Ang K, et al.  (2012) Mediator acts upstream of the transcriptional activator gal4. PLoS Biol 10(3):e1001290
Grandin N, et al.  (2012) Genetic and Physical Interactions between Tel2 and the Med15 Mediator Subunit in Saccharomyces cerevisiae. PLoS One 7(1):e30451
Peng J and Zhou JQ  (2012) The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance. Nucleic Acids Res 40(2):581-93
Wahba L, et al.  (2011) RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability. Mol Cell 44(6):978-88
Garcia A, et al.  (2010) Sub1 Globally Regulates RNA Polymerase II C-Terminal Domain Phosphorylation. Mol Cell Biol 30(21):5180-93
Libuda DE and Winston F  (2010) Alterations in DNA replication and histone levels promote histone gene amplification in Saccharomyces cerevisiae. Genetics 184(4):985-97
Zheng J, et al.  (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
Bennett CB, et al.  (2008) Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction. PLoS ONE 3(1):e1448
Qi Y, et al.  (2008) Finding friends and enemies in an enemies-only network: A graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions. Genome Res 18(12):1991-2004
Saguez C, et al.  (2008) Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation. Mol Cell 31(1):91-103
Pal B, et al.  (2007) SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae. Mol Biol Cell 18(2):426-40
Krasley E, et al.  (2006) Regulation of the Oxidative Stress Response Through Slt2p-Dependent Destruction of Cyclin C in Saccharomyces cerevisiae. Genetics 172(3):1477-86
Singh H, et al.  (2006) A functional module of yeast mediator that governs the dynamic range of heat-shock gene expression. Genetics 172(4):2169-84
Bose S, et al.  (2005) Genetic factors that regulate the attenuation of the general stress response of yeast. Genetics 169(3):1215-26
Chang YW, et al.  (2004) The Ras/PKA signaling pathway directly targets the Srb9 protein, a component of the general RNA polymerase II transcription apparatus. Mol Cell 15(1):107-16
Green SR and Johnson AD  (2004) Promoter-dependent roles for the Srb10 cyclin-dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae. Mol Biol Cell 15(9):4191-202
Hallberg M, et al.  (2004) Site-specific Srb10-dependent phosphorylation of the yeast Mediator subunit Med2 regulates gene expression from the 2-microm plasmid. Proc Natl Acad Sci U S A 101(10):3370-5
Lallet S, et al.  (2004) Heat shock-induced degradation of Msn2p, a Saccharomyces cerevisiae transcription factor, occurs in the nucleus. Mol Genet Genomics 272(3):353-62
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Wilcox CB, et al.  (2004) Genetic interactions with C-terminal domain (CTD) kinases and the CTD of RNA Pol II suggest a role for ESS1 in transcription initiation and elongation in Saccharomyces cerevisiae. Genetics 167(1):93-105
Zhang Z and Reese JC  (2004) Redundant mechanisms are used by Ssn6-Tup1 in repressing chromosomal gene transcription in Saccharomyces cerevisiae. J Biol Chem 279(38):39240-50
Balciunas D, et al.  (2003) Functional interactions within yeast mediator and evidence of differential subunit modifications. J Biol Chem 278(6):3831-9
Schaft D, et al.  (2003) The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation. Nucleic Acids Res 31(10):2475-82
Davie JK, et al.  (2002) Histone-dependent association of Tup1-Ssn6 with repressed genes in vivo. Mol Cell Biol 22(3):693-703
Jablonowski D and Schaffrath R  (2002) Saccharomyces cerevisiae RNA polymerase II is affected by Kluyveromyces lactis zymocin. J Biol Chem 277(29):26276-80
Conlan RS and Tzamarias D  (2001) Sfl1 functions via the co-repressor Ssn6-Tup1 and the cAMP-dependent protein kinase Tpk2. J Mol Biol 309(5):1007-15
Liu HY, et al.  (2001) Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme. J Biol Chem 276(10):7541-8
Tansey WP  (2001) Transcriptional activation: risky business. Genes Dev 15(9):1045-50
Rohde JR, et al.  (2000) Multiple signals regulate GAL transcription in yeast. Mol Cell Biol 20(11):3880-6
Balciunas D, et al.  (1999) The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression. Proc Natl Acad Sci U S A 96(2):376-81