HXK2/YGL253W Literature Guide Help

Other names published for HXK2: HEX1, HKB, SCI2, hexokinase 2, YGL253W

HXK2 - Genetic Interactions (40)

ReferenceOther Genes Addressed
Castermans D, et al.  (2012) Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast. Cell Res 22(6):1058-77
Searle JS, et al.  (2011) Proteins in the Nutrient-Sensing and DNA Damage Checkpoint Pathways Cooperate to Restrain Mitotic Progression following DNA Damage. PLoS Genet 7(7):e1002176
Kummel A, et al.  (2010) Differential glucose repression in common yeast strains in response to HXK2 deletion. FEMS Yeast Res 10(3):322-32
Pelaez R, et al.  (2010) Functional domains of yeast hexokinase 2. Biochem J 432(1):181-90
Noubhani A, et al.  (2009) The trehalose pathway regulates mitochondrial respiratory chain content through hexokinase 2 and cAMP in Saccharomyces cerevisiae. J Biol Chem 284(40):27229-34
Pelaez R, et al.  (2009) Nuclear Export of the Yeast Hexokinase 2 Protein Requires the Xpo1 (Crm1)-dependent Pathway. J Biol Chem 284(31):20548-55
Riesen M and Morgan A  (2009) Calorie restriction reduces rDNA recombination independently of rDNA silencing. Aging Cell 8(6):624-632
Berthels NJ, et al.  (2008) Correlation between glucose/fructose discrepancy and hexokinase kinetic properties in different Saccharomyces cerevisiae wine yeast strains. Appl Microbiol Biotechnol 77(5):1083-91
Carvalho RS, et al.  (2008) Obtaining and selection of hexokinases-less strains of Saccharomyces cerevisiae for production of ethanol and fructose from sucrose. Appl Microbiol Biotechnol 77(5):1131-7
Schuurmans JM, et al.  (2008) Physiological and transcriptional characterization of Saccharomyces cerevisiae strains with modified expression of catabolic regulators. FEMS Yeast Res 8(1):26-34
Van de Velde S and Thevelein JM  (2008) Cyclic AMP-protein kinase A and Snf1 signaling mechanisms underlie the superior potency of sucrose for induction of filamentation in Saccharomyces cerevisiae. Eukaryot Cell 7(2):286-93
Belinchon MM and Gancedo JM  (2007) Different signalling pathways mediate glucose induction of SUC2, HXT1 and pyruvate decarboxylase in yeast. FEMS Yeast Res 7(1):40-7
Belinchon MM and Gancedo JM  (2007) Glucose controls multiple processes in Saccharomyces cerevisiae through diverse combinations of signaling pathways. FEMS Yeast Res 7(6):808-18
Easlon E, et al.  (2007) The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension. J Biol Chem 282(9):6161-71
Sarma NJ, et al.  (2007) Glucose-responsive regulators of gene expression in Saccharomyces cerevisiae function at the nuclear periphery via a reverse recruitment mechanism. Genetics 175(3):1127-35
Cho JI, et al.  (2006) Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta 224(3):598-611
Kaeberlein M, et al.  (2006) Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science 312(5778):1312; author reply 1312
Kingsbury JM, et al.  (2006) Role of nitrogen and carbon transport, regulation, and metabolism genes for Saccharomyces cerevisiae survival in vivo. Eukaryot Cell 5(5):816-24
Kang HA, et al.  (2005) Characteristics of Saccharomyces cerevisiae gal1 Delta and gal1 Delta hxk2 Delta mutants expressing recombinant proteins from the GAL promoter. Biotechnol Bioeng 89(6):619-29
Lamming DW, et al.  (2005) HST2 mediates SIR2-independent life-span extension by calorie restriction. Science 309(5742):1861-4
Hung GC, et al.  (2004) Degradation of the gluconeogenic enzymes fructose-1,6-bisphosphatase and malate dehydrogenase is mediated by distinct proteolytic pathways and signaling events. J Biol Chem 279(47):49138-50
Kaeberlein M, et al.  (2004) Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol 2(9):E296
Lascaris R, et al.  (2004) Overexpression of HAP4 in glucose-derepressed yeast cells reveals respiratory control of glucose-regulated genes. Microbiology 150(Pt 4):929-34
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Giots F, et al.  (2003) Inorganic phosphate is sensed by specific phosphate carriers and acts in concert with glucose as a nutrient signal for activation of the protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 47(4):1163-81
Miseta A, et al.  (2003) A Saccharomyces cerevisiae mutant unable to convert glucose to glucose-6-phosphate accumulates excessive glucose in the endoplasmic reticulum due to core oligosaccharide trimming. Eukaryot Cell 2(3):534-41
Laht S, et al.  (2002) Cloning and characterization of glucokinase from a methylotrophic yeast Hansenula polymorpha: different effects on glucose repression in H. polymorpha and Saccharomyces cerevisiae. Gene 296(1-2):195-203
Salgado AP, et al.  (2002) Relationship between protein kinase C and derepression of different enzymes. FEBS Lett 532(3):324-32
De Silva-Udawatta MN and Cannon JF  (2001) Roles of trehalose phosphate synthase in yeast glycogen metabolism and sporulation. Mol Microbiol 40(6):1345-56
Nilsson A, et al.  (2001) The catabolic capacity of Saccharomyces cerevisiae is preserved to a higher extent during carbon compared to nitrogen starvation. Yeast 18(15):1371-81