FOB1/YDR110W Literature Guide Help

Other names published for FOB1: HRM1, YDR110W

FOB1 - Genetic Interactions (57)

ReferenceOther Genes Addressed
Medvedik O, et al.  (2007) MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLoS Biol 5(10):e261
Smith DL Jr, et al.  (2007) Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins. Aging Cell 6(5):649-62
Torres-Rosell J, et al.  (2007) Anaphase onset before complete DNA replication with intact checkpoint responses. Science 315(5817):1411-5
Calzari L, et al.  (2006) The Histone Deubiquitinating Enzyme Ubp10 Is Involved in rDNA Locus Control in Saccharomyces cerevisiae by Affecting Sir2p Association. Genetics 174(4):2249-54
Grenetier S, et al.  (2006) CTD kinase I is required for the integrity of the rDNA tandem array. Nucleic Acids Res 34(17):4996-5006
Johzuka K, et al.  (2006) Condensin loaded onto the replication fork barrier site in the rRNA gene repeats during S phase in a FOB1-dependent fashion to prevent contraction of a long repetitive array in Saccharomyces cerevisiae. Mol Cell Biol 26(6):2226-36
Kaeberlein M, et al.  (2006) Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science 312(5778):1312; author reply 1312
Machin F, et al.  (2006) Transcription of ribosomal genes can cause nondisjunction. J Cell Biol 173(6):893-903
Tsuchiya M, et al.  (2006) Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast. Aging Cell 5(6):505-14
Budd ME, et al.  (2005) A network of multi-tasking proteins at the DNA replication fork preserves genome stability. PLoS Genet 1(6):e61
Kaeberlein M, et al.  (2005) Genes determining yeast replicative life span in a long-lived genetic background. Mech Ageing Dev 126(4):491-504
Kaeberlein M, et al.  (2005) Increased life span due to calorie restriction in respiratory-deficient yeast. PLoS Genet 1(5):e69
Kaeberlein M, et al.  (2005) Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 310(5751):1193-6
Lamming DW, et al.  (2005) HST2 mediates SIR2-independent life-span extension by calorie restriction. Science 309(5742):1861-4
Bessler JB and Zakian VA  (2004) The amino terminus of the Saccharomyces cerevisiae DNA helicase Rrm3p modulates protein function altering replication and checkpoint activity. Genetics 168(3):1205-18
Kaeberlein M, et al.  (2004) Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol 2(9):E296
Torres JZ, et al.  (2004) Local chromatin structure at the ribosomal DNA causes replication fork pausing and genome instability in the absence of the S. cerevisiae DNA helicase Rrm3p. Genes Dev 18(5):498-503
Benguria A, et al.  (2003) Sir2p suppresses recombination of replication forks stalled at the replication fork barrier of ribosomal DNA in Saccharomyces cerevisiae. Nucleic Acids Res 31(3):893-8
Lin SS, et al.  (2003) Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing. J Biol Chem 278(15):13390-7
Weitao T, et al.  (2003) Dna2 helicase/nuclease causes replicative fork stalling and double-strand breaks in the ribosomal DNA of Saccharomyces cerevisiae. J Biol Chem 278(25):22513-22
Weitao T, et al.  (2003) Evidence that yeast SGS1, DNA2, SRS2, and FOB1 interact to maintain rDNA stability. Mutat Res 532(1-2):157-72
Hoopes LL, et al.  (2002) Mutations in DNA replication genes reduce yeast life span. Mol Cell Biol 22(12):4136-46
Merker RJ and Klein HL  (2002) hpr1Delta affects ribosomal DNA recombination and cell life span in Saccharomyces cerevisiae. Mol Cell Biol 22(2):421-9
Lin SJ, et al.  (2000) Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289(5487):2126-8
Kaeberlein M, et al.  (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13(19):2570-80
Oakes M, et al.  (1999) Transcription factor UAF, expansion and contraction of ribosomal DNA (rDNA) repeats, and RNA polymerase switch in transcription of yeast rDNA. Mol Cell Biol 19(12):8559-69
Kobayashi T, et al.  (1998) Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I. Genes Dev 12(24):3821-30