YFH1/YDL120W Literature Guide Help

Other names published for YFH1: YDL120W

YFH1 - Genetic Interactions (28)

ReferenceOther Genes Addressed
Lefevre S, et al.  (2012) Oxidative stress induces mitochondrial fragmentation in frataxin-deficient cells. Biochem Biophys Res Commun 418(2):336-41
Lefevre S, et al.  (2012) The yeast metacaspase is implicated in oxidative stress response in frataxin-deficient cells. FEBS Lett 586(2):143-8
Yoon H, et al.  (2012) Mutation in the Fe-S scaffold protein Isu bypasses frataxin deletion. Biochem J 441(1):473-80
Bedekovics T, et al.  (2011) Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent manner. J Biol Chem 286(47):40878-88
Seguin A, et al.  (2011) Co-precipitation of Phosphate and Iron Limits Mitochondrial Phosphate Availability in Saccharomyces cerevisiae Lacking the Yeast Frataxin Homologue (YFH1). J Biol Chem 286(8):6071-9
Vaubel RA, et al.  (2011) Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells. J Biol Chem 286(46):40232-45
Yoon H, et al.  (2011) Rim2, a pyrimidine nucleotide exchanger, is needed for iron utilization in mitochondria. Biochem J 440(1):137-46
Gonzalez-Cabo P, et al.  (2010) Flavin adenine dinucleotide rescues the phenotype of frataxin deficiency. PLoS One 5(1):e8872
Seguin A, et al.  (2010) Evidence that yeast frataxin is not an iron storage protein in vivo. Biochim Biophys Acta 1802(6):531-538
Irazusta V, et al.  (2008) Major targets of iron-induced protein oxidative damage in frataxin-deficient yeasts are magnesium-binding proteins. Free Radic Biol Med 44(9):1712-1723
Wang T and Craig EA  (2008) Binding of yeast frataxin to the scaffold for fe-s cluster biogenesis, isu. J Biol Chem 283(18):12674-9
Zhang Y, et al.  (2006) Mrs3p, Mrs4p, and frataxin provide iron for Fe-S cluster synthesis in mitochondria. J Biol Chem 281(32):22493-502
Gonzalez-Cabo P, et al.  (2005) Frataxin interacts functionally with mitochondrial electron transport chain proteins. Hum Mol Genet 14(15):2091-8
Zhang Y, et al.  (2005) Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis. J Biol Chem 280(20):19794-807
Aloria K, et al.  (2004) Iron-induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo. EMBO Rep 5(11):1096-101
Chen OS, et al.  (2004) Transcription of the yeast iron regulon does not respond directly to iron but rather to iron-sulfur cluster biosynthesis. J Biol Chem 279(28):29513-8
Ramazzotti A, et al.  (2004) Mitochondrial functional interactions between frataxin and Isu1p, the iron-sulfur cluster scaffold protein, in Saccharomyces cerevisiae. FEBS Lett 557(1-3):215-20
Santos R, et al.  (2004) Candida albicans lacking the frataxin homologue: a relevant yeast model for studying the role of frataxin. Mol Microbiol 54(2):507-19
Karthikeyan G, et al.  (2003) Reduction in frataxin causes progressive accumulation of mitochondrial damage. Hum Mol Genet 12(24):3331-42
Kucej M and Foury F  (2003) Iron toxicity protection by truncated Ras2 GTPase in yeast strain lacking frataxin. Biochem Biophys Res Commun 310(3):986-91
Lesuisse E, et al.  (2003) Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1). Hum Mol Genet 12(8):879-89
Chen OS, et al.  (2002) Genetic analysis of iron citrate toxicity in yeast: implications for mammalian iron homeostasis. Proc Natl Acad Sci U S A 99(26):16922-7
Foury F and Roganti T  (2002) Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain. J Biol Chem 277(27):24475-83
Karthikeyan G, et al.  (2002) The mitochondrial protein frataxin prevents nuclear damage. Hum Mol Genet 11(11):1351-62
Chen OS and Kaplan J  (2001) YFH1-mediated iron homeostasis is independent of mitochondrial respiration. FEBS Lett 509(1):131-4
Chen OS and Kaplan J  (2000) CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation. J Biol Chem 275(11):7626-32
Branda SS, et al.  (1999) Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae. Hum Mol Genet 8(6):1099-110
Strain J, et al.  (1998) Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. Identification of proteins predicted to mediate iron-sulfur cluster assembly. J Biol Chem 273(47):31138-44