Other names published for CDC4: SCF ubiquitin ligase complex subunit CDC4, YFL009W
CDC4 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Cell Cycle Phase Involved
- Cellular Location
- Function/Process
- Genetic Interactions
- Mutants/Phenotypes
- Regulation of
- Regulatory Role
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
CDC4 - Genetic Interactions (35)
| Reference | Other Genes Addressed |
|---|---|
| Landry BD, et al. (2012) F-box protein specificity for g1 cyclins is dictated by subcellular localization. PLoS Genet 8(7):e1002851 | |
| Liu Q, et al. (2011) SCFCdc4 Enables Mating Type Switching in Yeast by Cyclin-Dependent Kinase-Mediated Elimination of the Ash1 Transcriptional Repressor. Mol Cell Biol 31(3):584-98 | |
| Vendrell A, et al. (2011) Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase.LID - 10.1038/embor.2011.154 [doi] EMBO Rep () | |
| Aghajan M, et al. (2010) Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nat Biotechnol 28(7):738-42 | |
| Cappell SD, et al. (2010) Systematic analysis of essential genes reveals important regulators of G protein signaling. Mol Cell 38(5):746-57 | |
| Chee MK and Haase SB (2010) B-cyclin/CDKs regulate mitotic spindle assembly by phosphorylating kinesins-5 in budding yeast. PLoS Genet 6():e1000935 | |
| McLellan J, et al. (2009) Synthetic Lethal Genetic Interactions That Decrease Somatic Cell Proliferation in Caenorhabditis elegans Identify the Alternative RFCCTF18 as a Candidate Cancer Drug Target. Mol Biol Cell 20(24):5306-13 | |
| Mehta S, et al. (2009) Domain architecture of the regulators of calcineurin (RCANs) and identification of a divergent RCAN in yeast. Mol Cell Biol 29(10):2777-93 | |
| Sarkar S, et al. (2006) DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta. EMBO J 25(6):1285-94 | |
| Cui Z, et al. (2002) Cdc4 is involved in the transcriptional control of OCH1, a gene encoding alpha-1,6-mannosyltransferase in Saccharomyces cerevisiae. Yeast 19(1):69-77 | |
| Huang JN, et al. (2001) Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p. J Cell Biol 154(1):85-94 | |
| Blondel M, et al. (2000) Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in saccharomyces cerevisiae. Genetics 155(3):1033-44 | |
| Goh PY and Surana U (1999) Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae. Mol Cell Biol 19(8):5512-22 | |
| Haase SB and Reed SI (1999) Evidence that a free-running oscillator drives G1 events in the budding yeast cell cycle. Nature 401(6751):394-7 | |
| Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 | |
| Patton EE, et al. (1998) Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Genes Dev 12(5):692-705 | |
| Sanchez-Diaz A, et al. (1998) The Cdk inhibitors p25rum1 and p40SIC1 are functional homologues that play similar roles in the regulation of the cell cycle in fission and budding yeast. J Cell Sci 111 ( Pt 6)():843-51 | |
| Drury LS, et al. (1997) The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast. EMBO J 16(19):5966-76 | |
| Feldman RM, et al. (1997) A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91(2):221-30 | |
| Henchoz S, et al. (1997) Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev 11(22):3046-60 | |
| Lydall D and Weinert T (1997) G2/M checkpoint genes of Saccharomyces cerevisiae: further evidence for roles in DNA replication and/or repair. Mol Gen Genet 256(6):638-51 | |
| Verma R, et al. (1997) SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities. Mol Biol Cell 8(8):1427-37 | |
| Wassmann K and Ammerer G (1997) Overexpression of the G1-cyclin gene CLN2 represses the mating pathway in Saccharomyces cerevisiae at the level of the MEKK Ste11. J Biol Chem 272(20):13180-8 | |
| Knapp D, et al. (1996) The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1. Mol Cell Biol 16(10):5701-7 | |
| Siede W, et al. (1996) Cloning and characterization of RAD17, a gene controlling cell cycle responses to DNA damage in Saccharomyces cerevisiae. Nucleic Acids Res 24(9):1669-75 | |
| Bai C, et al. (1994) Human cyclin F. EMBO J 13(24):6087-98 | |
| Jackson AL, et al. (1993) Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein. Mol Cell Biol 13(5):2899-908 | |
| Smith SA, et al. (1992) SCM4, a gene that suppresses mutant cdc4 function in budding yeast. Mol Gen Genet 235(2-3):285-91 | |
| Dutcher SK and Hartwell LH (1983) Genes that act before conjugation to prepare the Saccharomyces cerevisiae nucleus for caryogamy. Cell 33(1):203-10 | |
| Dutcher SK and Hartwell LH (1983) Test for temporal or spatial restrictions in gene product function during the cell division cycle. Mol Cell Biol 3(7):1255-65 |




