TOR2/YKL203C Literature Guide Help

Other names published for TOR2: DRR2, YKL203C

TOR2 - Genetic Interactions (32)

ReferenceOther Genes Addressed
Cardon CM, et al.  (2012) PAS Kinase Promotes Cell Survival and Growth Through Activation of Rho1. Sci Signal 5(209):ra9
Pagan-Mercado G, et al.  (2012) Functional and genetic interactions of TOR in the budding yeast Saccharomyces cerevisiae with myosin type II-deficiency (myo1Delta). BMC Cell Biol 13(1):13
Pracheil T, et al.  (2012) TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae. Genetics 190(4):1325-39
Rai R, et al.  (2011) Small Ubiquitin-related Modifier Ligase Activity of Mms21 Is Required for Maintenance of Chromosome Integrity during the Unperturbed Mitotic Cell Division Cycle in Saccharomyces cerevisiae. J Biol Chem 286(16):14516-30
Roelants FM, et al.  (2011) Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(48):19222-7
Limson MV and Sweder KS  (2010) Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases. Toxicol Sci 113(1):77-84
Roelants FM, et al.  (2010) A protein kinase network regulates the function of aminophospholipid flippases. Proc Natl Acad Sci U S A 107(1):34-9
Tran LT, et al.  (2010) TORC1 kinase and the S-phase cyclin Clb5 collaborate to promote mitotic spindle assembly and DNA replication in S. cerevisiae. Curr Genet 56(6):479-93
Nakashima A, et al.  (2008) The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase. PLoS ONE 3(5):e2223
Schoner D, et al.  (2008) Annotating novel genes by integrating synthetic lethals and genomic information. BMC Syst Biol 2:3
Zurita-Martinez SA, et al.  (2007) Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae. Genetics 176(4):2139-50
Mulet JM, et al.  (2006) Mutual antagonism of target of rapamycin and calcineurin signaling. J Biol Chem 281(44):33000-7
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Kabir MA, et al.  (2005) Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae. Yeast 22(3):219-39
Kamada Y, et al.  (2005) Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Mol Cell Biol 25(16):7239-48
Audhya A, et al.  (2004) Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. EMBO J 23(19):3747-57
Monteiro G and Netto LE  (2004) Glucose repression of PRX1 expression is mediated by Tor1p and Ras2p through inhibition of Msn2/4p in Saccharomyces cerevisiae. FEMS Microbiol Lett 241(2):221-8
Morales-Johansson H, et al.  (2004) Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4. J Biol Chem 279(38):39604-10
Goehring AS, et al.  (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell 14(11):4329-41
Chan TF, et al.  (2000) A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR). Proc Natl Acad Sci U S A 97(24):13227-32
Beeler T, et al.  (1998) The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2+-sensitive csg2Delta mutant. J Biol Chem 273(46):30688-94
Bickle M, et al.  (1998) Cell wall integrity modulates RHO1 activity via the exchange factor ROM2. EMBO J 17(8):2235-45
Helliwell SB, et al.  (1998) TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. Genetics 148(1):99-112
Helliwell SB, et al.  (1998) The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Curr Biol 8(22):1211-4
Noda T and Ohsumi Y  (1998) Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J Biol Chem 273(7):3963-6
Fiorentino DF and Crabtree GR  (1997) Characterization of Saccharomyces cerevisiae dna2 mutants suggests a role for the helicase late in S phase. Mol Biol Cell 8(12):2519-37
Schmidt A, et al.  (1997) The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell 88(4):531-42
Barbet NC, et al.  (1996) TOR controls translation initiation and early G1 progression in yeast. Mol Biol Cell 7(1):25-42
Schmidt A, et al.  (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proc Natl Acad Sci U S A 93(24):13780-5
Helliwell SB, et al.  (1994) TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Mol Biol Cell 5(1):105-18