APN1/YKL114C Literature Guide Help

Other names published for APN1: DNA-(apurinic or apyrimidinic site) lyase APN1, YKL114C

APN1 - Genetic Interactions (75)

ReferenceOther Genes Addressed
Collura A, et al.  (2012) Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11(3):294-303
Lazzaro F, et al.  (2012) RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA. Mol Cell 45(1):99-110
Morris LP, et al.  (2012) Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans. DNA Repair (Amst) 11(9):753-65
Reis AM, et al.  (2012) Targeted detection of in vivo endogenous DNA base damage reveals preferential base excision repair in the transcribed strand. Nucleic Acids Res 40(1):206-19
Sobol Z and Schiestl RH  (2012) Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity. Environ Mol Mutagen 53(2):94-100
Wurtele H, et al.  (2012) Histone H3 lysine 56 acetylation and the response to DNA replication fork damage. Mol Cell Biol 32(1):154-72
Kim N, et al.  (2011) The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites. DNA Repair (Amst) 10(12):1262-71
Lada AG, et al.  (2011) Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast. Biochemistry (Mosc) 76(1):131-46
Ma W, et al.  (2011) Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease. PLoS Genet 7(4):e1002059
Daley JM, et al.  (2010) Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair. DNA Repair (Amst) 9(6):690-9
Degrandi TH, et al.  (2010) Evaluation of the cytotoxicity, genotoxicity and mutagenicity of diphenyl ditelluride in several biological models. Mutagenesis 25(3):257-69
Kim N and Jinks-Robertson S  (2010) Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair. Mol Cell Biol 30(13):3206-15
Latypov VF, et al.  (2010) [The Rdh54 protein role in regulation of DNA repair in yeast Saccharomyces cerevisiae] Genetika 46(2):194-202
Manikova D, et al.  (2010) Investigations on the role of base excision repair and non-homologous end-joining pathways in sodium selenite-induced toxicity and mutagenicity in Saccharomyces cerevisiae. Mutagenesis 25(2):155-62
Matuo R, et al.  (2010) DNA repair pathways involved in repair of lesions induced by 5-fluorouracil and its active metabolite FdUMP. Biochem Pharmacol 79(2):147-53
Northam MR, et al.  (2010) Participation of DNA polymerase {zeta} in replication of undamaged DNA in Saccharomyces cerevisiae. Genetics 184(1):27-42
Steininger S, et al.  (2010) A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair. Nucleic Acids Res 38(6):1853-65
Swartzlander DB, et al.  (2010) Regulation of base excision repair: Ntg1 nuclear and mitochondrial dynamic localization in response to genotoxic stress. Nucleic Acids Res 38(12):3963-74
Kaniak A, et al.  (2009) Msh1p counteracts oxidative lesion-induced instability of mtDNA and stimulates mitochondrial recombination in Saccharomyces cerevisiae. DNA Repair (Amst) 8(3):318-29
Kim N and Jinks-Robertson S  (2009) dUTP incorporation into genomic DNA is linked to transcription in yeast. Nature 459(7250):1150-3
Pogorzala L, et al.  (2009) Evidence that msh1p plays multiple roles in mitochondrial base excision repair. Genetics 182(3):699-709
van der Kemp PA, et al.  (2009) PCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae. Nucleic Acids Res 37(8):2549-59
Conde F and San-Segundo PA  (2008) Role of Dot1 in the response to alkylating DNA damage in Saccharomyces cerevisiae: regulation of DNA damage tolerance by the error-prone polymerases Polzeta/Rev1. Genetics 179(3):1197-210
Degtyareva NP, et al.  (2008) Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae. Mol Cell Biol 28(17):5432-45
Erlich RL, et al.  (2008) Anc1, a Protein Associated with Multiple Transcription Complexes, Is Involved in Postreplication Repair Pathway in S. cerevisiae. PLoS ONE 3(11):e3717
Ma W, et al.  (2008) Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis. Nucleic Acids Res 36(6):1836-46
Flott S, et al.  (2007) Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast. Mol Cell Biol 27(18):6433-45
Hoskins J and Scott Butler J  (2007) Evidence for distinct DNA- and RNA-based mechanisms of 5-fluorouracil cytotoxicity in Saccharomyces cerevisiae. Yeast 24(10):861-70
Ragu S, et al.  (2007) Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death. Proc Natl Acad Sci U S A 104(23):9747-52
Rusyn I, et al.  (2007) Transcriptional Networks in S. cerevisiae Linked to an Accumulation of Base Excision Repair Intermediates. PLoS ONE 2(11):e1252