RAD27/YKL113C Literature Guide Help

Other names published for RAD27: ERC11, RTH1, FEN1, YKL113C

RAD27 - Genetic Interactions (94)

ReferenceOther Genes Addressed
Jin YH, et al.  (2003) Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick. J Biol Chem 278(3):1626-33
Liu Y and Bambara RA  (2003) Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion. J Biol Chem 278(16):13728-39
Ooi SL, et al.  (2003) DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray. Nat Genet 35(3):277-86
Sun X, et al.  (2003) Complementary functions of the Saccharomyces cerevisiae Rad2 family nucleases in Okazaki fragment maturation, mutation avoidance, and chromosome stability. DNA Repair (Amst) 2(8):925-40
Hoopes LL, et al.  (2002) Mutations in DNA replication genes reduce yeast life span. Mol Cell Biol 22(12):4136-46
Lewis LK, et al.  (2002) Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics 160(1):49-62
McInnis M, et al.  (2002) Epistatic analysis of the roles of the RAD27 and POL4 gene products in DNA base excision repair in S. cerevisiae. DNA Repair (Amst) 1(4):311-5
Parenteau J and Wellinger RJ  (2002) Differential processing of leading- and lagging-strand ends at Saccharomyces cerevisiae telomeres revealed by the absence of Rad27p nuclease. Genetics 162(4):1583-94
Tran PT, et al.  (2002) Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae. DNA Repair (Amst) 1(11):895-912
Debrauwere H, et al.  (2001) Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity. Proc Natl Acad Sci U S A 98(15):8263-9
Jin YH, et al.  (2001) The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. Proc Natl Acad Sci U S A 98(9):5122-7
Klein HL  (2001) Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae. Genetics 157(2):557-65
Moreau S, et al.  (2001) Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism. Genetics 159(4):1423-33
Negritto MC, et al.  (2001) Novel function of Rad27 (FEN-1) in restricting short-sequence recombination. Mol Cell Biol 21(7):2349-58
Qiu J, et al.  (2001) Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair. J Biol Chem 276(7):4901-8
Tong AH, et al.  (2001) Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294(5550):2364-8
Budd ME and Campbell JL  (2000) The pattern of sensitivity of yeast dna2 mutants to DNA damaging agents suggests a role in DSB and postreplication repair pathways. Mutat Res 459(3):173-86
Chen JZ, et al.  (2000) Mutational spectrum analysis of RNase H(35) deficient Saccharomyces cerevisiae using fluorescence-based directed termination PCR. Nucleic Acids Res 28(18):3649-56
Hansen RJ, et al.  (2000) Sensitivity of a S. cerevisiae RAD27 deletion mutant to DNA-damaging agents and in vivo complementation by the human FEN-1 gene. Mutat Res 461(3):243-8
Kirchner JM, et al.  (2000) A DNA polymerase epsilon mutant that specifically causes +1 frameshift mutations within homonucleotide runs in yeast. Genetics 155(4):1623-32
Moreau S, et al.  (1999) The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol Cell Biol 19(1):556-66
Parenteau J and Wellinger RJ  (1999) Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27. Mol Cell Biol 19(6):4143-52
Qiu J, et al.  (1999) Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol Cell Biol 19(12):8361-71
Wu X and Wang Z  (1999) Relationships between yeast Rad27 and Apn1 in response to apurinic/apyrimidinic (AP) sites in DNA. Nucleic Acids Res 27(4):956-62
Xie Y, et al.  (1999) Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loader. Genetics 151(2):499-509
Johnson RE, et al.  (1998) Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication. Curr Genet 34(1):21-9
Merrill BJ and Holm C  (1998) The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis. Genetics 148(2):611-24
Symington LS  (1998) Homologous recombination is required for the viability of rad27 mutants. Nucleic Acids Res 26(24):5589-95
Budd ME and Campbell JL  (1997) A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function. Mol Cell Biol 17(4):2136-42
Tishkoff DX, et al.  (1997) A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell 88(2):253-63