RNR1/YER070W Literature Guide Help

Other names published for RNR1: CRT7, RIR1, SDS12, ribonucleotide-diphosphate reductase subunit RNR1, YER070W

RNR1 - Genetic Interactions (35)

ReferenceOther Genes Addressed
Ahmad F, et al.  (2012) Role of arginine 293 and glutamine 288 in communication between catalytic and allosteric sites in yeast ribonucleotide reductase. J Mol Biol 419(5):315-29
Poon BP and Mekhail K  (2012) Effects of Perinuclear Chromosome Tethers in the Telomeric URA3/5FOA System Reflect Changes to Gene Silencing and not Nucleotide Metabolism. Front Genet 3():144
Dosil M  (2011) Ribosome synthesis-unrelated functions of the preribosomal factor Rrp12 in cell cycle progression and the DNA damage response. Mol Cell Biol 31(12):2422-38
Ma E, et al.  (2011) Giant yeast cells with nonrecyclable ribonucleotide reductase. Mol Genet Genomics 285(5):415-25
Tsaponina O, et al.  (2011) Ixr1 Is Required for the Expression of the Ribonucleotide Reductase Rnr1 and Maintenance of dNTP Pools. PLoS Genet 7(5):e1002061
Andreson BL, et al.  (2010) The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage. Nucleic Acids Res 38(19):6490-501
Koren A, et al.  (2010) MRC1-dependent scaling of the budding yeast DNA replication timing program. Genome Res 20(6):781-90
Kumar D, et al.  (2010) Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint. Nucleic Acids Res 38(12):3975-83
Stumpf JD, et al.  (2010) mip1 Containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae. Hum Mol Genet 19(11):2123-33
Singh I, et al.  (2009) Stringent mating-type-regulated auxotrophy increases the accuracy of systematic genetic interaction screens with Saccharomyces cerevisiae mutant arrays. Genetics 181(1):289-300
Chabes A and Stillman B  (2007) Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 104(4):1183-8
Hartman JL 4th  (2007) Buffering of deoxyribonucleotide pool homeostasis by threonine metabolism. Proc Natl Acad Sci U S A 104(28):11700-5
Kaplan Y and Kupiec M  (2007) A role for the yeast cell cycle/splicing factor Cdc40 in the G(1)/S transition. Curr Genet 51(2):123-40
Lebedeva MA and Shadel GS  (2007) Cell cycle- and ribonucleotide reductase-driven changes in mtDNA copy number influence mtDNA Inheritance without compromising mitochondrial gene expression. Cell Cycle 6(16):2048-57
Weinberger M, et al.  (2007) DNA replication stress is a determinant of chronological lifespan in budding yeast. PLoS One 2(8):e748
Zhang Z, et al.  (2007) Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1. Proc Natl Acad Sci U S A 104(7):2217-22
Baruffini E, et al.  (2006) Genetic and chemical rescue of the Saccharomyces cerevisiae phenotype induced by mitochondrial DNA polymerase mutations associated with progressive external ophthalmoplegia in humans. Hum Mol Genet 15(19):2846-55
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
Woolstencroft RN, et al.  (2006) Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length. J Cell Sci 119(Pt 24):5178-92
Carter CD, et al.  (2005) Loss of SOD1 and LYS7 sensitizes Saccharomyces cerevisiae to hydroxyurea and DNA damage agents and downregulates MEC1 pathway effectors. Mol Cell Biol 25(23):10273-85
Michel AH, et al.  (2005) Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing. Genes Dev 19(10):1199-210
O'Rourke TW, et al.  (2005) Differential involvement of the related DNA helicases Pif1p and Rrm3p in mtDNA point mutagenesis and stability. Gene 354():86-92
Raithatha SA and Stuart DT  (2005) Meiosis-specific regulation of the Saccharomyces cerevisiae S-phase cyclin CLB5 is dependent on MluI cell cycle box (MCB) elements in its promoter but is independent of MCB-binding factor activity. Genetics 169(3):1329-42
Toussaint M, et al.  (2005) Limited TTP supply affects telomere length regulation in a telomerase-independent fashion. Nucleic Acids Res 33(2):704-13
Dubacq C, et al.  (2004) The protein kinase Snf1 is required for tolerance to the ribonucleotide reductase inhibitor hydroxyurea. Mol Cell Biol 24(6):2560-72
Betz JL, et al.  (2002) Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Mol Genet Genomics 268(2):272-85
Amin NS, et al.  (2001) exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair. Mol Cell Biol 21(15):5142-55
Tong AH, et al.  (2001) Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294(5550):2364-8
Desany BA, et al.  (1998) Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev 12(18):2956-70
Vanderstraeten S, et al.  (1998) The role of 3'-5' exonucleolytic proofreading and mismatch repair in yeast mitochondrial DNA error avoidance. J Biol Chem 273(37):23690-7