ISC1/YER019W Literature Guide Help

Other names published for ISC1: inositol phosphosphingolipid phospholipase, YER019W

ISC1 - Genetic Interactions (11)

ReferenceOther Genes Addressed
Barbosa AD, et al.  (2012) Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging. Mech Ageing Dev 133(5):317-30
Short MK, et al.  (2012) The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism. PLoS One 7(7):e39428
Barbosa AD, et al.  (2011) Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells. Mol Microbiol 81(2):515-27
Tripathi K, et al.  (2011) Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics 189(2):533-47
Guan XL, et al.  (2009) Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology. Mol Biol Cell 20(7):2083-95
Matmati N, et al.  (2009) Hydroxyurea Sensitivity Reveals a Role for ISC1 in the Regulation of G2/M. J Biol Chem 284(13):8241-6
Almeida T, et al.  (2008) Isc1p Plays a Key Role in Hydrogen Peroxide Resistance and Chronological Lifespan through Modulation of Iron Levels and Apoptosis. Mol Biol Cell 19(3):865-876
Mousley CJ, et al.  (2008) Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell 19(11):4785-803
Cowart LA, et al.  (2006) Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae. Biochem J 393(Pt 3):733-40
Tabuchi M, et al.  (2006) The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation. Mol Cell Biol 26(15):5861-75
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13