MEC1/YBR136W Literature Guide Help

Other names published for MEC1: ESR1, SAD3, RAD31, YBR136W

MEC1 - Genetic Interactions (190)

ReferenceOther Genes Addressed
Chuang CN, et al.  (2012) Mek1 stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during yeast meiosis. Nucleic Acids Res 40(22):11416-27
Collura A, et al.  (2012) Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11(3):294-303
Davidson MB, et al.  (2012) Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype. EMBO J 31(4):895-907
Garcia-Rodriguez N, et al.  (2012) Impaired manganese metabolism causes mitotic misregulation. J Biol Chem 287(22):18717-29
Hashash N, et al.  (2012) Topoisomerase II- and Condensin-Dependent Breakage of MEC1(ATR)-Sensitive Fragile Sites Occurs Independently of Spindle Tension, Anaphase, or Cytokinesis. PLoS Genet 8(10):e1002978
Liang D, et al.  (2012) Histone dosage regulates DNA damage sensitivity in a checkpoint-independent manner by the homologous recombination pathway. Nucleic Acids Res 40(19):9604-20
Manfrini N, et al.  (2012) G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. Mol Cell Biol 32(24):4971-85
Ribaud V, et al.  (2012) DNA-end capping by the budding yeast transcription factor and subtelomeric binding protein Tbf1. EMBO J 31(1):138-49
Srividya I, et al.  (2012) Yeast transcription termination factor rtt103 functions in DNA damage response. PLoS One 7(2):e31288
Tittel-Elmer M, et al.  (2012) Cohesin association to replication sites depends on rad50 and promotes fork restart. Mol Cell 48(1):98-108
Au TJ, et al.  (2011) ATP-dependent chromatin remodeling factors tune S phase checkpoint activity. Mol Cell Biol 31(22):4454-63
Bermejo R, et al.  (2011) The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell 146(2):233-46
Chen X, et al.  (2011) Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.LID - 10.1038/nsmb.2105 [doi] Nat Struct Mol Biol ()
Gangavarapu V, et al.  (2011) Requirement of replication checkpoint protein kinases mec1/rad53 for postreplication repair in yeast.LID - 10.1128/mBio.00079-11 [doi]LID - e00079-11 [pii] MBio 2(3)
Germann SM, et al.  (2011) Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination. DNA Repair (Amst) 10(2):210-24
Hashash N, et al.  (2011) Regulation of fragile sites expression in budding yeast by MEC1, RRM3 and hydroxyurea. J Cell Sci 124(Pt 2):181-5
Ho HC and Burgess SM  (2011) Pch2 Acts through Xrs2 and Tel1/ATM to Modulate Interhomolog Bias and Checkpoint Function during Meiosis. PLoS Genet 7(11):e1002351
Leon Ortiz AM, et al.  (2011) Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. DNA Repair (Amst) 10(5):506-17
Li XC and Tye BK  (2011) Ploidy Dictates Repair Pathway Choice under DNA Replication Stress. Genetics 187(4):1031-40
Nolt JK, et al.  (2011) PP2A (Cdc)55 is required for multiple events during meiosis I. Cell Cycle 10(9):1420-34
Rai R, et al.  (2011) Small Ubiquitin-related Modifier Ligase Activity of Mms21 Is Required for Maintenance of Chromosome Integrity during the Unperturbed Mitotic Cell Division Cycle in Saccharomyces cerevisiae. J Biol Chem 286(16):14516-30
Reha-Krantz LJ, et al.  (2011) Drug-sensitive DNA polymerase d reveals a role for mismatch repair in checkpoint activation in yeast. Genetics 189(4):1211-24
Sanvisens N, et al.  (2011) Regulation of ribonucleotide reductase in response to iron deficiency. Mol Cell 44(5):759-69
Searle JS, et al.  (2011) Proteins in the Nutrient-Sensing and DNA Damage Checkpoint Pathways Cooperate to Restrain Mitotic Progression following DNA Damage. PLoS Genet 7(7):e1002176
Tao R, et al.  (2011) Xbp1-mediated histone H4 deacetylation contributes to DNA double-strand break repair in yeast. Cell Res 21(11):1619-33
Bandyopadhyay S, et al.  (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
Burgess RJ, et al.  (2010) A role for Gcn5 in replication-coupled nucleosome assembly. Mol Cell 37(4):469-80
Fasullo M, et al.  (2010) Elevated dNTP levels suppress hyper-recombination in Saccharomyces cerevisiae S-phase checkpoint mutants. Nucleic Acids Res 38(4):1195-203
Gao H, et al.  (2010) Telomerase Recruitment in Saccharomyces cerevisiae Is Not Dependent on Tel1-Mediated Phosphorylation of Cdc13. Genetics 186(4):1147-59
Giannattasio M, et al.  (2010) Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation. Mol Cell 40(1):50-62