PDR5/YOR153W Literature Guide Help

Other names published for PDR5: LEM1, YDR1, STS1, ATP-binding cassette multidrug transporter PDR5, YOR153W

PDR5 LITERATURE TOPICS

PDR5 - Fungal Related Genes/Proteins (53)

ReferenceOther Genes Addressed
Zhang Y, et al.  (2012) CDR4 is the major contributor to azole resistance among four Pdr5p-like ABC transporters in Neurospora crassa. Fungal Biol 116(7):848-54
Muller LA, et al.  (2011) Genome-wide association analysis of clinical vs. nonclinical origin provides insights into Saccharomyces cerevisiae pathogenesis. Mol Ecol 20(19):4085-97
Paul S, et al.  (2011) Regulation of the CgPdr1 Transcription Factor from the Pathogen Candida glabrata. Eukaryot Cell 10(2):187-97
Rutledge RM, et al.  (2011) Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: A molecular modeling study. J Struct Biol 173(2):333-44
Sharma M and Prasad R  (2011) The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. Antimicrob Agents Chemother 55(10):4834-43
Guan W, et al.  (2010) Antagonistic Changes in Sensitivity to Antifungal Drugs by Mutations of an Important ABC Transporter Gene in a Fungal Pathogen. PLoS One 5(6):e11309
Miranda MN, et al.  (2010) The serine/threonine protein phosphatase Sit4p activates multidrug resistance in Saccharomyces cerevisiae. FEMS Yeast Res 10(6):674-86
Kolaczkowski M, et al.  (2009) New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters. Antimicrob Agents Chemother 53(4):1516-27
Lamping E, et al.  (2009) Abc1p Is a Multidrug Efflux Transporter That Tips the Balance in Favor of Innate Azole Resistance in Candida krusei. Antimicrob Agents Chemother 53(2):354-369
Seret ML, et al.  (2009) Combined phylogeny and neighborhood analysis of the evolution of the ABC transporters conferring multiple drug resistance in hemiascomycete yeasts. BMC Genomics 10:459
Sharma M, et al.  (2009) Curcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals. Antimicrob Agents Chemother 53(8):3256-65
Tsao S, et al.  (2009) Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance. Antimicrob Agents Chemother 53(4):1344-52
Banerjee D, et al.  (2008) Responses of pathogenic and nonpathogenic yeast species to steroids reveal the functioning and evolution of multidrug resistance transcriptional networks. Eukaryot Cell 7(1):68-77
Torelli R, et al.  (2008) The ATP-binding cassette transporter-encoding gene CgSNQ2 is contributing to the CgPDR1-dependent azole resistance of Candida glabrata. Mol Microbiol 68(1):186-201
Lamping E, et al.  (2007) Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae. Eukaryot Cell 6(7):1150-65
Shen H, et al.  (2007) Fcr1p Inhibits Development of Fluconazole Resistance in Candida albicans by Abolishing CDR1 Induction. Biol Pharm Bull 30(1):68-73
Tanabe K, et al.  (2007) Inhibition of fungal ABC transporters by unnarmicin A and unnarmicin C, novel cyclic peptides from marine bacterium. Biochem Biophys Res Commun 364(4):990-5
De Hertogh B, et al.  (2006) Emergence of species-specific transporters during evolution of the hemiascomycete phylum. Genetics 172(2):771-81
Li XC, et al.  (2006) Capisterones A and B, which Enhance Fluconazole Activity in Saccharomyces cerevisiae, from the Marine Green Alga Penicillus capitatus. J Nat Prod 69(4):542-6
Costa Cda S, et al.  (2005) Transporters in the Paracoccidioides brasiliensis transcriptome: insights on drug resistance. Genet Mol Res 4(2):390-408
Hiraga K, et al.  (2005) Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae. Biochem Biophys Res Commun 328(4):1119-25
Lee SA, et al.  (2005) Intracellular trafficking of fluorescently tagged proteins associated with pathogenesis in Candida albicans. Med Mycol 43(5):423-30
Wada S, et al.  (2005) Phosphorylation of candida glabrata ATP-binding cassette transporter Cdr1p regulates drug efflux activity and ATPase stability. J Biol Chem 280(1):94-103
Yamamoto S, et al.  (2005) A new function of isonitrile as an inhibitor of the Pdr5p multidrug ABC transporter in Saccharomyces cerevisiae. Biochem Biophys Res Commun 330(2):622-8
Kaur R, et al.  (2004) Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria. Antimicrob Agents Chemother 48(5):1600-13
Takacova M, et al.  (2004) KNQ1, a Kluyveromyces lactis gene encoding a drug efflux permease. Curr Genet 45(1):1-8
Wolfger H, et al.  (2004) The yeast Pdr15p ATP-binding cassette (ABC) protein is a general stress response factor implicated in cellular detoxification. J Biol Chem 279(12):11593-9
Izumikawa K, et al.  (2003) Function of Candida glabrata ABC transporter gene, PDH1. Yeast 20(3):249-61
Rogers PD and Barker KS  (2003) Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates. Antimicrob Agents Chemother 47(4):1220-7
Keeven J, et al.  (2002) PDR2 Gain-of-function mutations eliminate the need for Pdr1 and require the UBP6 product for resistance to translational inhibitors. Curr Genet 41(1):11-9