YKU80/YMR106C Literature Guide Help

Other names published for YKU80: HDF2, YMR106C

YKU80 - Function/Process (75)

ReferenceOther Genes Addressed
Kalifa L, et al.  (2012) Mitochondrial genome maintenance: roles for nuclear nonhomologous end-joining proteins in Saccharomyces cerevisiae. Genetics 190(3):951-64
Luciano P, et al.  (2012) RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts. EMBO J 31(8):2034-46
Bahmed K, et al.  (2011) End-processing during non-homologous end-joining: a role for exonuclease 1. Nucleic Acids Res 39(3):970-8
Lopez CR, et al.  (2011) Ku Must Load Directly onto the Chromosome End in Order to Mediate Its Telomeric Functions. PLoS Genet 7(8):e1002233
Svensson JP, et al.  (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5(1):157
Bahmed K, et al.  (2010) Yeast Tdp1 regulates the fidelity of nonhomologous end joining. Proc Natl Acad Sci U S A 107(9):4057-62
Shim EY, et al.  (2010) Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks. EMBO J 29(19):3370-80
Halas A, et al.  (2009) Evaluation of the roles of Pol zeta and NHEJ in starvation-associated spontaneous mutagenesis in the yeast Saccharomyces cerevisiae. Curr Genet 55(3):245-51
Loney ER, et al.  (2009) Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae. Epigenetics Chromatin 2(1):18
Schober H, et al.  (2009) Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes Dev 23(8):928-38
Clerici M, et al.  (2008) The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle. EMBO Rep 9(8):810-8
Ebrahimi H and Donaldson AD  (2008) Release of yeast telomeres from the nuclear periphery is triggered by replication and maintained by suppression of Ku-mediated anchoring. Genes Dev 22(23):3363-3374
Patterson EE and Fox CA  (2008) The Ku Complex in Silencing the Cryptic Mating-Type Loci of Saccharomyces cerevisiae. Genetics 180(2):771-83
Ponnusamy S, et al.  (2008) Regulation of Telomere Length by Fatty Acid Elongase 3 in Yeast: INVOLVEMENT OF INOSITOL PHOSPHATE METABOLISM AND Ku70/80 FUNCTION. J Biol Chem 283(41):27514-24
Raisner RM and Madhani HD  (2008) Genomewide Screen for Negative Regulators of Sirtuin Activity in Saccharomyces cerevisiae Reveals 40 Loci and Links to Metabolism. Genetics 179(4):1933-44
Ribes-Zamora A, et al.  (2007) Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions. Nat Struct Mol Biol 14(4):301-7
Sabourin M, et al.  (2007) Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol Cell 27(4):550-61
Tam AT, et al.  (2007) Telomere-related functions of yeast KU in the repair of bleomycin-induced DNA damage. Biochem Biophys Res Commun 357(3):800-803
Zhang Y, et al.  (2007) Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination. Nat Struct Mol Biol 14(7):639-46
Banerjee S, et al.  (2006) Suppression of gross chromosomal rearrangements by yKu70-yKu80 heterodimer through DNA damage checkpoints. Proc Natl Acad Sci U S A 103(6):1816-21
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
Palmbos PL, et al.  (2005) Mutations of the Yku80 C terminus and Xrs2 FHA domain specifically block yeast nonhomologous end joining. Mol Cell Biol 25(24):10782-90
Pardo B and Marcand S  (2005) Rap1 prevents telomere fusions by nonhomologous end joining. EMBO J 24(17):3117-27
Ruan C, et al.  (2005) The DNA repair protein yKu80 regulates the function of recombination enhancer during yeast mating type switching. Mol Cell Biol 25(19):8476-85
Shim EY, et al.  (2005) The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks. Mol Cell Biol 25(10):3934-44
Taddei A, et al.  (2005) Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression. Novartis Found Symp 264:140-56; discussion 156-65, 227-30
Fisher TS, et al.  (2004) Cell cycle-dependent regulation of yeast telomerase by Ku. Nat Struct Mol Biol 11(12):1198-205
Gartenberg MR, et al.  (2004) Sir-mediated repression can occur independently of chromosomal and subnuclear contexts. Cell 119(7):955-67
Roy R, et al.  (2004) Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing. J Biol Chem 279(1):86-94
Smolikov S, et al.  (2004) ELG1, a regulator of genome stability, has a role in telomere length regulation and in silencing. Proc Natl Acad Sci U S A 101(6):1656-61