XRS2/YDR369C Literature Guide Help

Other names published for XRS2: YDR369C

XRS2 - Function/Process (83)

ReferenceOther Genes Addressed
Cremona CA, et al.  (2012) Extensive DNA damage-induced sumoylation contributes to replication and repair and acts in addition to the mec1 checkpoint. Mol Cell 45(3):422-32
Kalifa L, et al.  (2012) Mitochondrial genome maintenance: roles for nuclear nonhomologous end-joining proteins in Saccharomyces cerevisiae. Genetics 190(3):951-64
Zhang Y, et al.  (2012) Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell 48(2):254-65
Chan CY, et al.  (2011) Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae. Mol Genet Genomics 285(6):471-84
Ho HC and Burgess SM  (2011) Pch2 Acts through Xrs2 and Tel1/ATM to Modulate Interhomolog Bias and Checkpoint Function during Meiosis. PLoS Genet 7(11):e1002351
Nakai W, et al.  (2011) Chromosome integrity at a double-strand break requires exonuclease 1 and MRX. DNA Repair (Amst) 10(1):102-10
Cejka P, et al.  (2010) DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2. Nature 467(7311):112-6
Kaochar S, et al.  (2010) Checkpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 107(50):21605-10
Nicolette ML, et al.  (2010) Mre11-Rad50-Xrs2 and Sae2 promote 5' strand resection of DNA double-strand breaks. Nat Struct Mol Biol 17(12):1478-85
Niu H, et al.  (2010) Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae. Nature 467(7311):108-11
Steininger S, et al.  (2010) A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair. Nucleic Acids Res 38(6):1853-65
Bonetti D, et al.  (2009) Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres. Mol Cell 35(1):70-81
Ma Y and Greider CW  (2009) Kinase-independent functions of TEL1 in telomere maintenance. Mol Cell Biol 29(18):5193-202
Tittel-Elmer M, et al.  (2009) The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress. EMBO J 28(8):1142-56
Lee K, et al.  (2008) Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations. Nature 454(7203):543-6
Matsuzaki K, et al.  (2008) Forkhead-Associated Domain of Yeast Xrs2, a Homolog of Human Nbs1, Promotes Nonhomologous End Joining Through Interaction With a Ligase IV Partner Protein, Lif1. Genetics 179(1):213-25
Steininger S, et al.  (2008) Xrs2 facilitates crossovers during DNA double-strand gap repair in yeast. DNA Repair (Amst) 7(9):1563-77
Zhu Z, et al.  (2008) Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134(6):981-94
Chen XL, et al.  (2007) Topoisomerase I-Dependent Viability Loss in Saccharomyces cerevisiae Mutants Defective in Both SUMO Conjugation and DNA Repair. Genetics 177(1):17-30
Gangavarapu V, et al.  (2007) Requirement of RAD52 Group Genes for Postreplication Repair of UV-Damaged DNA in Saccharomyces cerevisiae. Mol Cell Biol 27(21):7758-64
Ghosal G and Muniyappa K  (2007) The Characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 Complex Reveals that Rad50 Negatively Regulates Mre11 Endonucleolytic but not the Exonucleolytic Activity. J Mol Biol 372(4):864-82
Hirano Y and Sugimoto K  (2007) Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends. Mol Biol Cell 18(6):2026-36
Lengsfeld BM, et al.  (2007) Sae2 Is an Endonuclease that Processes Hairpin DNA Cooperatively with the Mre11/Rad50/Xrs2 Complex. Mol Cell 28(4):638-51
Sabourin M, et al.  (2007) Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol Cell 27(4):550-61
Yuen KW, et al.  (2007) Systematic genome instability screens in yeast and their potential relevance to cancer. Proc Natl Acad Sci U S A 104(10):3925-30
Zhang Y, et al.  (2007) Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination. Nat Struct Mol Biol 14(7):639-46
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
Grenon M, et al.  (2006) Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation. FEMS Yeast Res 6(5):836-47
Andrews CA and Clarke DJ  (2005) MRX (Mre11/Rad50/Xrs2) mutants reveal dual intra-S-phase checkpoint systems in budding yeast. Cell Cycle 4(8):1073-7
Chen L, et al.  (2005) Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast. J Biol Chem 280(4):2620-7