UBR1/YGR184C Literature Guide Help

Other names published for UBR1: PTR1, E3 ubiquitin-protein ligase UBR1, YGR184C

UBR1 - Function/Process (29)

ReferenceOther Genes Addressed
Khosrow-Khavar F, et al.  (2012) The yeast ubr1 ubiquitin ligase participates in a prominent pathway that targets cytosolic thermosensitive mutants for degradation. G3 (Bethesda) 2(5):619-28
Heck JW, et al.  (2010) Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1. Proc Natl Acad Sci U S A 107(3):1106-11
Hwang CS, et al.  (2010) The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases. Nat Cell Biol 12(12):1177-85
Nillegoda NB, et al.  (2010) Ubr1 and ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins. Mol Biol Cell 21(13):2102-16
Prasad R, et al.  (2010) A nucleus-based quality control mechanism for cytosolic proteins. Mol Biol Cell 21(13):2117-27
Eisele F and Wolf DH  (2008) Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1. FEBS Lett 582(30):4143-6
Kyoda K, et al.  (2004) DBRF-MEGN method: an algorithm for deducing minimum equivalent gene networks from large-scale gene expression profiles of gene deletion mutants. Bioinformatics 20(16):2662-75
Sanchez-Diaz A, et al.  (2004) Rapid depletion of budding yeast proteins by fusion to a heat-inducible degron. Sci STKE 2004(223):PL8
Lupas AN and Koretke KK  (2003) Bioinformatic analysis of ClpS, a protein module involved in prokaryotic and eukaryotic protein degradation. J Struct Biol 141(1):77-83
Du F, et al.  (2002) Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain. Proc Natl Acad Sci U S A 99(22):14110-5
Turner SD, et al.  (2002) The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription. Mol Cell Biol 22(12):4011-9
Xie Y and Varshavsky A  (2002) UFD4 lacking the proteasome-binding region catalyses ubiquitination but is impaired in proteolysis. Nat Cell Biol 4(12):1003-7
Hauser M, et al.  (2001) Multiplicity and regulation of genes encoding peptide transporters in Saccharomyces cerevisiae. Mol Membr Biol 18(1):105-12
Rao H, et al.  (2001) Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature 410(6831):955-9
Buonomo SB, et al.  (2000) Disjunction of homologous chromosomes in meiosis I depends on proteolytic cleavage of the meiotic cohesin Rec8 by separin. Cell 103(3):387-98
Tongaonkar P, et al.  (2000) Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome. Mol Cell Biol 20(13):4691-8
Turner GC and Varshavsky A  (2000) Detecting and measuring cotranslational protein degradation in vivo. Science 289(5487):2117-20
Turner GC, et al.  (2000) Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature 405(6786):579-83
Xie Y and Varshavsky A  (2000) Physical association of ubiquitin ligases and the 26S proteasome. Proc Natl Acad Sci U S A 97(6):2497-502
Kwon YT, et al.  (1999) Bivalent inhibitor of the N-end rule pathway. J Biol Chem 274(25):18135-9
Suzuki T and Varshavsky A  (1999) Degradation signals in the lysine-asparagine sequence space. EMBO J 18(21):6017-26
Thompson DA and Stahl FW  (1999) Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Genetics 153(2):621-41
Xie Y and Varshavsky A  (1999) The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain. EMBO J 18(23):6832-44
Xie Y and Varshavsky A  (1999) The N-end rule pathway is required for import of histidine in yeast lacking the kinesin-like protein Cin8p. Curr Genet 36(3):113-23
Alagramam K, et al.  (1995) A recognition component of the ubiquitin system is required for peptide transport in Saccharomyces cerevisiae. Mol Microbiol 15(2):225-34
Sharon G, et al.  (1991) RAD6 gene product of Saccharomyces cerevisiae requires a putative ubiquitin protein ligase (E3) for the ubiquitination of certain proteins. J Biol Chem 266(24):15890-4
Bartel B, et al.  (1990) The recognition component of the N-end rule pathway. EMBO J 9(10):3179-89
Bachmair A and Varshavsky A  (1989) The degradation signal in a short-lived protein. Cell 56(6):1019-32
Bachmair A, et al.  (1986) In vivo half-life of a protein is a function of its amino-terminal residue. Science 234(4773):179-86