Other names published for TOP1: MAK1, MAK17, DNA topoisomerase 1, YOL006C
TOP1 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
TOP1 - Function/Process (53)
| Reference | Other Genes Addressed |
|---|---|
| Garcia-Rubio ML and Aguilera A (2012) Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes. Nucleic Acids Res 40(3):1050-64 | |
| Joshi RS, et al. (2012) Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res 40(16):7907-15 | |
| French SL, et al. (2011) Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes. Mol Cell Biol 31(3):482-94 | |
| Kim N, et al. (2011) Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I. Science 332(6037):1561-4 | |
| Lippert MJ, et al. (2011) Role for topoisomerase 1 in transcription-associated mutagenesis in yeast. Proc Natl Acad Sci U S A 108(2):698-703 | |
| Sperling AS, et al. (2011) Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proc Natl Acad Sci U S A 108(31):12693-8 | |
| Takahashi T, et al. (2011) Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(2):692-7 | |
| Cesarini E, et al. (2010) RNA Polymerase I Transcription Silences Noncoding RNAs at the Ribosomal DNA Locus in Saccharomyces cerevisiae. Eukaryot Cell 9(2):325-35 | |
| El Hage A, et al. (2010) Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev 24(14):1546-58 | |
| Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 | |
| Di Felice F, et al. (2008) Nucleosomes represent a physical barrier for cleavage activity of DNA topoisomerase I in vivo. Biochem J 409(3):651-6 | |
| Han S and Kim D (2008) Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways. PLoS Comput Biol 4(8):e1000162 | |
| Lotito L, et al. (2008) Global transcription regulation by DNA topoisomerase I in exponentially growing Saccharomyces cerevisiae cells: activation of telomere-proximal genes by TOP1 deletion. J Mol Biol 377(2):311-22 | |
| Takahashi Y, et al. (2008) Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genet 4(10):e1000215 | |
| Chen XL, et al. (2007) Topoisomerase I-Dependent Viability Loss in Saccharomyces cerevisiae Mutants Defective in Both SUMO Conjugation and DNA Repair. Genetics 177(1):17-30 | |
| Cline SD and Hanawalt PC (2006) Topoisomerase deficiencies subtly enhance global genomic repair of ultraviolet-induced DNA damage in Saccharomyces cerevisiae. DNA Repair (Amst) 5(5):611-7 | |
| Gambus A, et al. (2006) GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol 8(4):358-66 | |
| Lebedeva N, et al. (2006) Trapping of DNA topoisomerase I on nick-containing DNA in cell free extracts of Saccharomyces cerevisiae. DNA Repair (Amst) 5(7):799-809 | |
| Salceda J, et al. (2006) Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA. EMBO J 25(11):2575-83 | |
| Di Felice F, et al. (2005) FOB1 affects DNA topoisomerase I in vivo cleavages in the enhancer region of the Saccharomyces cerevisiae ribosomal DNA locus. Nucleic Acids Res 33(19):6327-37 | |
| Mercier G, et al. (2005) A haploid-specific transcriptional response to irradiation in Saccharomyces cerevisiae. Nucleic Acids Res 33(20):6635-43 | |
| Fiorani P, et al. (2004) The deubiquitinating enzyme Doa4p protects cells from DNA topoisomerase I poisons. J Biol Chem 279(20):21271-81 | |
| Rajeshkumar NV, et al. (2003) Induction of apoptosis in mouse and human carcinoma cell lines by Emblica officinalis polyphenols and its effect on chemical carcinogenesis. J Exp Clin Cancer Res 22(2):201-12 | |
| Redon C, et al. (2003) Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage. EMBO Rep 4(7):678-84 | |
| Gadal O, et al. (2002) Hmo1, an HMG-box protein, belongs to the yeast ribosomal DNA transcription system. EMBO J 21(20):5498-507 | |
| Liu C, et al. (2002) Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1. Proc Natl Acad Sci U S A 99(23):14970-5 | |
| Trigueros S and Roca J (2002) Failure to relax negative supercoiling of DNA is a primary cause of mitotic hyper-recombination in topoisomerase-deficient yeast cells. J Biol Chem 277(40):37207-11 | |
| Vance JR and Wilson TE (2002) Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage. Proc Natl Acad Sci U S A 99(21):13669-74 | |
| Mullen JR, et al. (2001) Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics 157(1):103-18 | |
| Nitiss JL, et al. (2001) Overexpression of type I topoisomerases sensitizes yeast cells to DNA damage. J Biol Chem 276(28):26708-14 |





