TIM22/YDL217C Literature Guide Help

Other names published for TIM22: YDL217C

TIM22 - Function/Process (26)

ReferenceOther Genes Addressed
Peixoto PM, et al.  (2007) Awaking TIM22, a dynamic ligand-gated channel for protein insertion in the mitochondrial inner membrane. J Biol Chem 282(26):18694-701
Brandner K, et al.  (2005) The carboxyl-terminal third of the dicarboxylate carrier is crucial for productive association with the inner membrane twin-pore translocase. J Biol Chem 280(7):6215-21
Vergnolle MA, et al.  (2005) A cryptic matrix targeting signal of the yeast ADP/ATP carrier normally inserted by the TIM22 complex is recognized by the TIM23 machinery. Biochem J 385(Pt 1):173-80
Yamano K, et al.  (2005) The phosphate carrier has an ability to be sorted to either the TIM22 pathway or the TIM23 pathway for its import into yeast mitochondria. J Biol Chem 280(11):10011-7
Curran SP, et al.  (2004) The role of Hot13p and redox chemistry in the mitochondrial TIM22 import pathway. J Biol Chem 279(42):43744-51
Vasiljev A, et al.  (2004) Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes. Mol Biol Cell 15(3):1445-58
Dunn CD and Jensen RE  (2003) Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA. Genetics 165(1):35-45
Dyall SD, et al.  (2003) The dynamic dimerization of the yeast ADP/ATP carrier in the inner mitochondrial membrane is affected by conserved cysteine residues. J Biol Chem 278(29):26757-64
Herrmann JM and Neupert W  (2003) Protein insertion into the inner membrane of mitochondria. IUBMB Life 55(4-5):219-25
Rehling P, et al.  (2003) Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane--a guided tour. J Mol Biol 326(3):639-57
Rehling P, et al.  (2003) Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science 299(5613):1747-51
Curran SP, et al.  (2002) The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier. EMBO J 21(5):942-53
Jensen RE and Dunn CD  (2002) Protein import into and across the mitochondrial inner membrane: role of the TIM23 and TIM22 translocons. Biochim Biophys Acta 1592(1):25-34
Kovermann P, et al.  (2002) Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel. Mol Cell 9(2):363-73
Bauer MF and Neupert W  (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80
Paschen SA and Neupert W  (2001) Protein import into mitochondria. IUBMB Life 52(3-5):101-12
Prohl C, et al.  (2001) The yeast mitochondrial carrier Leu5p and its human homologue Graves' disease protein are required for accumulation of coenzyme A in the matrix. Mol Cell Biol 21(4):1089-97
Rehling P, et al.  (2001) The mitochondrial import machinery for preproteins. Crit Rev Biochem Mol Biol 36(3):291-336
Davis AJ, et al.  (2000) Two intermembrane space TIM complexes interact with different domains of Tim23p during its import into mitochondria. J Cell Biol 150(6):1271-82
Kerscher O, et al.  (2000) Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane. Mol Biol Cell 11(1):103-16
Endres M, et al.  (1999) Transport of the ADP/ATP carrier of mitochondria from the TOM complex to the TIM22.54 complex. EMBO J 18(12):3214-21
Leuenberger D, et al.  (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22
Arnold I, et al.  (1998) Two distinct and independent mitochondrial targeting signals function in the sorting of an inner membrane protein, cytochrome c1. J Biol Chem 273(3):1469-76
Kerscher O, et al.  (1997) The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane. J Cell Biol 139(7):1663-75
Sirrenberg C, et al.  (1997) Functional cooperation and stoichiometry of protein translocases of the outer and inner membranes of mitochondria. J Biol Chem 272(47):29963-6
Sirrenberg C, et al.  (1996) Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22. Nature 384(6609):582-5