TIM17/YJL143W Literature Guide Help

Other names published for TIM17: MIM17, MPI2, SMS1, YJL143W

TIM17 - Function/Process (23)

ReferenceOther Genes Addressed
Popov-Celeketic D, et al.  (2011) Role of the import motor in insertion of transmembrane segments by the mitochondrial TIM23 complex. EMBO Rep 12(6):542-8
Iacovino M, et al.  (2009) The conserved translocase Tim17 prevents mitochondrial DNA loss. Hum Mol Genet 18(1):65-74
Becker D, et al.  (2008) In vitro analysis of the mitochondrial preprotein import machinery using recombinant precursor polypeptides. Methods Mol Biol 457():59-83
Popov-Celeketic D, et al.  (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80
Martinez-Caballero S, et al.  (2007) Tim17p regulates the twin pore structure and voltage gating of the mitochondrial protein import complex TIM23. J Biol Chem 282(6):3584-93
van der Laan M, et al.  (2007) Motor-free mitochondrial presequence translocase drives membrane integration of preproteins. Nat Cell Biol 9(10):1152-9
Chacinska A, et al.  (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29
Meier S, et al.  (2005) Conserved N-terminal negative charges in the Tim17 subunit of the TIM23 translocase play a critical role in the import of preproteins into mitochondria. J Biol Chem 280(9):7777-85
Rehling P, et al.  (2003) Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane--a guided tour. J Mol Biol 326(3):639-57
Milisav I, et al.  (2001) Modular structure of the TIM23 preprotein translocase of mitochondria. J Biol Chem 276(28):25856-61
Young L, et al.  (2001) Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science 291(5511):2135-8
Kurz M, et al.  (1999) Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway. Mol Biol Cell 10(7):2461-74
Lee CM, et al.  (1999) The DNA helicase, Hmi1p, is transported into mitochondria by a C-terminal cleavable targeting signal. J Biol Chem 274(30):20937-42
Moro F, et al.  (1999) The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix. EMBO J 18(13):3667-75
Schulke N, et al.  (1999) A multisubunit complex of outer and inner mitochondrial membrane protein translocases stabilized in vivo by translocation intermediates. J Biol Chem 274(32):22847-54
Folsch H, et al.  (1998) C- to N-terminal translocation of preproteins into mitochondria. EMBO J 17(22):6508-15
Dekker PJ, et al.  (1997) The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44. EMBO J 16(17):5408-19
Kerscher O, et al.  (1997) The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane. J Cell Biol 139(7):1663-75
Berthold J, et al.  (1995) The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system. Cell 81(7):1085-93
Blom J, et al.  (1995) Functional and physical interactions of components of the yeast mitochondrial inner-membrane import machinery (MIM). Eur J Biochem 232(1):309-14
Kubrich M, et al.  (1994) The polytopic mitochondrial inner membrane proteins MIM17 and MIM23 operate at the same preprotein import site. FEBS Lett 349(2):222-8
Maarse AC, et al.  (1994) Identification of the essential yeast protein MIM17, an integral mitochondrial inner membrane protein involved in protein import. FEBS Lett 349(2):215-21
Ryan KR, et al.  (1994) SMS1, a high-copy suppressor of the yeast mas6 mutant, encodes an essential inner membrane protein required for mitochondrial protein import. Mol Biol Cell 5(5):529-38