STE5/YDR103W Literature Guide Help

Other names published for STE5: HMD3, NUL3, YDR103W

STE5 - Function/Process (41)

ReferenceOther Genes Addressed
Malleshaiah MK, et al.  (2010) The scaffold protein Ste5 directly controls a switch-like mating decision in yeast. Nature 465(7294):101-5
Chapman SA and Asthagiri AR  (2009) Quantitative effect of scaffold abundance on signal propagation. Mol Syst Biol 5():313
Good M, et al.  (2009) The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation. Cell 136(6):1085-97
Mazor Y and Kupiec M  (2009) Developmentally regulated MAPK pathways modulate heterochromatin in Saccharomyces cerevisiae. Nucleic Acids Res 37(14):4839-49
Rensing L and Ruoff P  (2009) How can yeast cells decide between three activated MAP kinase pathways? A model approach. J Theor Biol 257(4):578-87
Tanaka H and Yi TM  (2009) Synthetic morphology using alternative inputs. PLoS One 4(9):e6946
Hao N, et al.  (2008) Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5. Mol Cell 30(5):649-56
Takahashi S and Pryciak PM  (2008) Membrane Localization of Scaffold Proteins Promotes Graded Signaling in the Yeast MAP Kinase Cascade. Curr Biol 18(16):1184-91
Strickfaden SC, et al.  (2007) A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway. Cell 128(3):519-31
Bhattacharyya RP, et al.  (2006) The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Science 311(5762):822-6
Garrenton LS, et al.  (2006) Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain. Genes Dev 20(14):1946-58
Schwartz MA and Madhani HD  (2006) Control of MAPK signaling specificity by a conserved residue in the MEK-binding domain of the yeast scaffold protein Ste5. Curr Genet 49(6):351-63
Titz B, et al.  (2006) Transcriptional activators in yeast. Nucleic Acids Res 34(3):955-67
Winters MJ, et al.  (2005) A membrane binding domain in the ste5 scaffold synergizes with gbetagamma binding to control localization and signaling in pheromone response. Mol Cell 20(1):21-32
Andersson J, et al.  (2004) Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J 23(13):2564-76
Flotho A, et al.  (2004) Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade. J Biol Chem 279(45):47391-401
Kyoda K, et al.  (2004) DBRF-MEGN method: an algorithm for deducing minimum equivalent gene networks from large-scale gene expression profiles of gene deletion mutants. Bioinformatics 20(16):2662-75
Maleri S, et al.  (2004) Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast. Mol Cell Biol 24(20):9221-38
Park SH, et al.  (2003) Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms. Science 299(5609):1061-4
Ptashne M and Gann A  (2003) Signal transduction. Imposing specificity on kinases. Science 299(5609):1025-7
Wang Y and Elion EA  (2003) Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components. Mol Biol Cell 14(6):2543-58
Lamson RE, et al.  (2002) Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20. Mol Cell Biol 22(9):2939-51
Bardwell AJ, et al.  (2001) A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission. J Biol Chem 276(13):10374-86
Harris K, et al.  (2001) Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins. Curr Biol 11(23):1815-24
Kunzler M, et al.  (2001) Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects. Genetics 157(3):1089-105
van Drogen F, et al.  (2001) MAP kinase dynamics in response to pheromones in budding yeast. Nat Cell Biol 3(12):1051-9
Choi YJ, et al.  (2000) Saccharomyces cerevisiae Ste5 is important for induction and substrate specificity of Fus3 MAP kinase in the pheromone signaling pathway. Mol Cells 10(3):301-8
Crosby JA, et al.  (2000) Constitutive activation of the Saccharomyces cerevisiae transcriptional regulator Ste12p by mutations at the amino-terminus. Yeast 16(15):1365-75
Sette C, et al.  (2000) Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein. Mol Biol Cell 11(11):4033-49
Choi KY, et al.  (1999) Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell 10(5):1553-68