SET2/YJL168C Literature Guide Help

Other names published for SET2: EZL1, KMT3, YJL168C

SET2 - Function/Process (36)

ReferenceOther Genes Addressed
Venkatesh S, et al.  (2012) Set2 methylation of histone H3 lysine?36 suppresses histone exchange on transcribed genes. Nature 489(7416):452-5
Churchman LS and Weissman JS  (2011) Nascent transcript sequencing visualizes transcription at nucleotide resolution. Nature 469(7330):368-73
Wlodarski T, et al.  (2011) Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome. PLoS One 6(8):e23168
Du HN and Briggs SD  (2010) A nucleosome surface formed by histone H4, H2A, and H3 residues is needed for proper histone H3 Lys36 methylation, histone acetylation, and repression of cryptic transcription. J Biol Chem 285(15):11704-13
Kim T and Buratowski S  (2009) Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5' transcribed regions. Cell 137(2):259-72
Pryde F, et al.  (2009) H3 k36 methylation helps determine the timing of cdc45 association with replication origins. PLoS One 4(6):e5882
Verzijlbergen KF, et al.  (2009) Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae. BMC Mol Biol 10:76
Biswas D, et al.  (2008) A Role for Chd1 and Set2 in Negatively Regulating DNA Replication in Saccharomyces cerevisiae. Genetics 178(2):649-59
Biswas D, et al.  (2008) Different genetic functions for the Rpd3(L) and Rpd3(S) complexes suggest competition between NuA4 and Rpd3(S). Mol Cell Biol 28(14):4445-58
Du HN, et al.  (2008) Histone H3 K36 methylation is mediated by a trans-histone methylation pathway involving an interaction between Set2 and histone H4. Genes Dev 22(20):2786-98
Merker JD, et al.  (2008) The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae. DNA Repair (Amst) 7(8):1298-308
Kim T and Buratowski S  (2007) Two Saccharomyces cerevisiae JmjC domain proteins demethylate histone H3 Lys36 in transcribed regions to promote elongation. J Biol Chem 282(29):20827-35
Biswas D, et al.  (2006) Opposing roles for Set2 and yFACT in regulating TBP binding at promoters. EMBO J 25(19):4479-89
Carrozza MJ, et al.  (2005) Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123(4):581-92
Giannattasio M, et al.  (2005) The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J Biol Chem 280(11):9879-86
Joshi AA and Struhl K  (2005) Eaf3 chromodomain interaction with methylated H3-K36 links histone deacetylation to Pol II elongation. Mol Cell 20(6):971-8
Keogh MC, et al.  (2005) Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell 123(4):593-605
Kizer KO, et al.  (2005) A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. Mol Cell Biol 25(8):3305-16
Morillon A, et al.  (2005) Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription. Mol Cell 18(6):723-34
Morohashi N, et al.  (2005) Effect of histone methyltransferase gene mutations on sporulation in S. cerevisiae. Nucleic Acids Symp Ser (Oxf)(49):325-6
Pokholok DK, et al.  (2005) Genome-wide map of nucleosome acetylation and methylation in yeast. Cell 122(4):517-27
Rao B, et al.  (2005) Dimethylation of histone H3 at lysine 36 demarcates regulatory and nonregulatory chromatin genome-wide. Mol Cell Biol 25(21):9447-59
Sheldon KE, et al.  (2005) A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation. Mol Cell 20(2):225-36
Jacobson SJ, et al.  (2004) Functional analyses of chromatin modifications in yeast. Methods Enzymol 377:3-55
Boa S, et al.  (2003) Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression. Yeast 20(9):827-35
Krogan NJ, et al.  (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12(6):1565-76
Krogan NJ, et al.  (2003) Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol 23(12):4207-18
Landry J, et al.  (2003) Set2-catalyzed methylation of histone H3 represses basal expression of GAL4 in Saccharomyces cerevisiae. Mol Cell Biol 23(17):5972-8
Li B, et al.  (2003) The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem 278(11):8897-903
Ng HH, et al.  (2003) The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B. J Biol Chem 278(36):33625-8