Other names published for SAC1: RSD1, phosphatidylinositol-3-phosphatase SAC1, YKL212W
SAC1 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Cellular Location
- Function/Process
- Genetic Interactions
- Mutants/Phenotypes
- Regulation of
- Regulatory Role
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Additional Information
SAC1 - Function/Process (30)
| Reference | Other Genes Addressed |
|---|---|
| Zhong S, et al. (2012) Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipids. Biochemistry 51(15):3170-7 | |
| Lorente-Rodriguez A and Barlowe C (2011) Requirement for Golgi-localized PI(4)P in fusion of COPII vesicles with Golgi compartments. Mol Biol Cell 22(2):216-29 | |
| Stefan CJ, et al. (2011) Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites. Cell 144(3):389-401 | |
| Hacioglu E, et al. (2010) The roles of thiol oxidoreductases in yeast replicative aging. Mech Ageing Dev 131(11-12):692-9 | |
| Abe F and Minegishi H (2008) Global screening of genes essential for growth in high-pressure and cold environments: searching for basic adaptive strategies using a yeast deletion library. Genetics 178(2):851-72 | |
| Faulhammer F, et al. (2005) Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p. J Cell Biol 168(2):185-91 | |
| Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 | |
| Tahirovic S, et al. (2005) Regulation of intracellular phosphatidylinositol-4-phosphate by the Sac1 lipid phosphatase. Traffic 6(2):116-30 | |
| Tahirovic S, et al. (2003) Role for lipid signaling and the cell integrity MAP kinase cascade in yeast septum biogenesis. Curr Genet 43(2):71-8 | |
| Wenk MR, et al. (2003) Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry. Nat Biotechnol 21(7):813-7 | |
| Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 | |
| Gary JD, et al. (2002) Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell 13(4):1238-51 | |
| Konrad G, et al. (2002) Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport. J Biol Chem 277(12):10547-54 | |
| Li X, et al. (2002) Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex. J Cell Biol 157(1):63-77 | |
| Foti M, et al. (2001) Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology. Mol Biol Cell 12(8):2396-411 | |
| Schorr M, et al. (2001) The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase. Curr Biol 11(18):1421-6 | |
| Hughes WE, et al. (2000) SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases. J Biol Chem 275(2):801-8 | |
| Hughes WE, et al. (2000) Sac phosphatase domain proteins. Biochem J 350 Pt 2():337-52 | |
| Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 | |
| Hama H, et al. (1999) Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae. J Biol Chem 274(48):34294-300 | |
| Hughes WE, et al. (1999) Mutations in the Saccharomyces cerevisiae gene SAC1 cause multiple drug sensitivity. Yeast 15(11):1111-24 | |
| Kochendorfer KU, et al. (1999) Sac1p plays a crucial role in microsomal ATP transport, which is distinct from its function in Golgi phospholipid metabolism. EMBO J 18(6):1506-15 | |
| Rivas MP, et al. (1999) Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. Mol Biol Cell 10(7):2235-50 | |
| Stock SD, et al. (1999) SEC14-dependent secretion in Saccharomyces cerevisiae. Nondependence on sphingolipid synthesis-coupled diacylglycerol production. J Biol Chem 274(19):12979-83 | |
| Boyum R and Guidotti G (1997) Sac1p of Saccharomyces cerevisiae is not involved in ATP release to the extracellular fluid. Biochem Biophys Res Commun 236(1):50-3 | |
| Kearns BG, et al. (1997) Essential role for diacylglycerol in protein transport from the yeast Golgi complex. Nature 387(6628):101-5 | |
| Mayinger P, et al. (1995) Sac1p mediates the adenosine triphosphate transport into yeast endoplasmic reticulum that is required for protein translocation. J Cell Biol 131(6 Pt 1):1377-86 | |
| Whitters EA, et al. (1993) SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J Cell Biol 122(1):79-94 | |
| Cleves AE, et al. (1989) Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function. J Cell Biol 109(6 Pt 1):2939-50 | |
| Novick P, et al. (1989) Suppressors of yeast actin mutations. Genetics 121(4):659-74 |





