RAD6/YGL058W Literature Guide Help

Other names published for RAD6: UBC2, PSO8, E2 ubiquitin-conjugating protein RAD6, YGL058W

RAD6 - Function/Process (107)

ReferenceOther Genes Addressed
Ha SW, et al.  (2012) The N-terminal domain of Rpn4 serves as a portable ubiquitin-independent degron and is recognized by specific 19S RP subunits. Biochem Biophys Res Commun 419(2):226-31
Rizzardi LF, et al.  (2012) DNA replication origin function is promoted by H3K4 di-methylation in Saccharomyces cerevisiae. Genetics 192(2):371-84
Weinberger L, et al.  (2012) Expression noise and acetylation profiles distinguish HDAC functions. Mol Cell 47(2):193-202
Svensson JP, et al.  (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5(1):157
Takahashi YH, et al.  (2011) Dot1 and Histone H3K79 Methylation in Natural Telomeric and HM Silencing. Mol Cell 42(1):118-26
Wang CY, et al.  (2011) The C-Terminus of Histone H2B Is Involved in Chromatin Compaction Specifically at Telomeres, Independently of Its Monoubiquitylation at Lysine 123. PLoS One 6(7):e22209
Heck JW, et al.  (2010) Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1. Proc Natl Acad Sci U S A 107(3):1106-11
Carlile CM, et al.  (2009) Synthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5. J Biol Chem 284(43):29326-34
Hishida T, et al.  (2009) RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light. Nature 457(7229):612-5
Kats ES, et al.  (2009) The Saccharomyces cerevisiae Rad6 postreplication repair and Siz1/Srs2 homologous recombination-inhibiting pathways process DNA damage that arises in asf1 mutants. Mol Cell Biol 29(19):5226-37
Kim J and Roeder RG  (2009) Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast. J Biol Chem 284(31):20582-92
Lundh F, et al.  (2009) Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter. Biochemistry 48(21):4497-505
Parker JL and Ulrich HD  (2009) Mechanistic analysis of PCNA poly-ubiquitylation by the ubiquitin protein ligases Rad18 and Rad5. EMBO J 28(23):3657-66
Yousef AF, et al.  (2009) Requirements for E1A dependent transcription in the yeast Saccharomyces cerevisiae. BMC Mol Biol 10:32
Fu Y, et al.  (2008) Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp. Cell 133(4):601-11
Iraqui I, et al.  (2008) Human peroxiredoxin PrxI is an orthologue of yeast Tsa1, capable of suppressing genome instability in Saccharomyces cerevisiae. Cancer Res 68(4):1055-63
Ju D, et al.  (2008) Genome-wide analysis identifies MYND-domain protein Mub1 as an essential factor for Rpn4 ubiquitylation. Mol Cell Biol 28(4):1404-12
Moertl S, et al.  (2008) Regulation of double-stranded DNA gap repair by the RAD6 pathway. DNA Repair (Amst) 7(11):1893-906
Nyswaner KM, et al.  (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214
Yousef AF, et al.  (2008) Coactivator requirements for p53-dependent transcription in the yeast Saccharomyces cerevisiae. Int J Cancer 122(4):942-6
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
Haracska L, et al.  (2006) Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. Proc Natl Acad Sci U S A 103(17):6477-82
Hiraishi H, et al.  (2006) Enhancement of Stress Tolerance in Saccharomyces cerevisiae by Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes. Biosci Biotechnol Biochem 70(11):2762-5
Ju D and Xie Y  (2006) Identification of the preferential ubiquitination site and ubiquitin-dependent degradation signal of Rpn4. J Biol Chem 281(16):10657-62
McIntyre J, et al.  (2006) Analysis of the spontaneous mutator phenotype associated with 20S proteasome deficiency in S. cerevisiae. Mutat Res 593(1-2):153-63
Pan X, et al.  (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81
Giannattasio M, et al.  (2005) The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J Biol Chem 280(11):9879-86
Guo Y, et al.  (2005) Expression of a human cytochrome p450 in yeast permits analysis of pathways for response to and repair of aflatoxin-induced DNA damage. Mol Cell Biol 25(14):5823-33
Huang ME and Kolodner RD  (2005) A biological network in Saccharomyces cerevisiae prevents the deleterious effects of endogenous oxidative DNA damage. Mol Cell 17(5):709-20
Keszenman DJ, et al.  (2005) RAD6 gene is involved in heat shock induction of bleomycin resistance in Saccharomyces cerevisiae. Environ Mol Mutagen 45(1):36-43