RAD53/YPL153C Literature Guide Help

Other names published for RAD53: LSD1, MEC2, SPK1, YPL153C

RAD53 - Function/Process (194)

ReferenceOther Genes Addressed
Covo S, et al.  (2012) RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition. DNA Repair (Amst) 11(3):317-23
De Piccoli G, et al.  (2012) Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases. Mol Cell 45(5):696-704
Manfrini N, et al.  (2012) G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. Mol Cell Biol 32(24):4971-85
Gangavarapu V, et al.  (2011) Requirement of replication checkpoint protein kinases mec1/rad53 for postreplication repair in yeast.LID - 10.1128/mBio.00079-11 [doi]LID - e00079-11 [pii] MBio 2(3)
Conde F, et al.  (2010) Regulation of tolerance to DNA alkylating damage by Dot1 and Rad53 in Saccharomyces cerevisiae. DNA Repair (Amst) 9(10):1038-49
Holzen TM and Sclafani R  (2010) Genetic interaction of RAD53 protein kinase with histones is important for DNA replication. Cell Cycle 9(23):4735-47
Kaochar S, et al.  (2010) Checkpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 107(50):21605-10
Lopez-Mosqueda J, et al.  (2010) Cdc5 blocks in vivo Rad53 activity, but not in situ activity (ISA). Cell Cycle 9(21):4266-8
Nguyen VC, et al.  (2010) Replication stress checkpoint signaling controls tRNA gene transcription. Nat Struct Mol Biol 17(8):976-81
Randell JC, et al.  (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol Cell 40(3):353-63
Zegerman P and Diffley JF  (2010) Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation. Nature 467(7314):474-8
Diani L, et al.  (2009) Saccharomyces CDK1 Phosphorylates Rad53 Kinase in Metaphase, Influencing Cellular Morphogenesis. J Biol Chem 284(47):32627-34
Enserink JM, et al.  (2009) Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae. J Cell Biol 185(3):423-37
Feng W, et al.  (2009) Centromere replication timing determines different forms of genomic instability in Saccharomyces cerevisiae checkpoint mutants during replication stress. Genetics 183(4):1249-60
Makovets S and Blackburn EH  (2009) DNA damage signalling prevents deleterious telomere addition at DNA breaks. Nat Cell Biol 11(11):1383-6
Truman AW, et al.  (2009) Mechanism of Mpk1 mitogen-activated protein kinase binding to the Swi4 transcription factor and its regulation by a novel caffeine-induced phosphorylation. Mol Cell Biol 29(24):6449-61
Usui T, et al.  (2009) Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization. Mol Cell 33(2):147-59
Barea F and Bonatto D  (2008) Relationships among carbohydrate intermediate metabolites and DNA damage and repair in yeast from a systems biology perspective. Mutat Res 642(1-2):43-56
Cartagena-Lirola H, et al.  (2008) Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. Mol Cell Biol 28(14):4480-93
Fasullo M, et al.  (2008) Stimulation of sister chromatid exchanges and mutation by aflatoxin B1-DNA adducts in Saccharomyces cerevisiae requires MEC1 (ATR), RAD53, and DUN1. Mol Carcinog 47(8):608-15
Jia-Lin Ma N and Stern DF  (2008) Regulation of the Rad53 protein kinase in signal amplification by oligomer assembly and disassembly. Cell Cycle 7(6):808-17
Lee H, et al.  (2008) Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade. Mol Cell 30(6):767-78
Morin I, et al.  (2008) Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response. EMBO J 27(18):2400-10
Ogi H, et al.  (2008) The role of the Saccharomyces cerevisiae Cdc7-Dbf4 complex in the replication checkpoint. Gene 414(1-2):32-40
Razidlo DF and Lahue RS  (2008) Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. DNA Repair (Amst) 7(4):633-40
Szyjka SJ, et al.  (2008) Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae. Genes Dev 22(14):1906-20
Ahnesorg P and Jackson SP  (2007) The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint. DNA Repair (Amst) 6(2):190-201
Chen SH, et al.  (2007) Mechanism of Dun1 activation by Rad53 phosphorylation in Saccharomyces cerevisiae. J Biol Chem 282(2):986-95
Da-Silva LF and Duncker BP  (2007) ORC function in late G1: maintaining the license for DNA replication. Cell Cycle 6(2):128-30
Dubrana K, et al.  (2007) The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast. J Cell Sci 120(Pt 23):4209-20