Other names published for PRP8: DBF3, DNA39, RNA8, SLT21, USA2, YHR165C
PRP8 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
PRP8 - Function/Process (39)
| Reference | Other Genes Addressed |
|---|---|
| Warkocki Z, et al. (2009) Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nat Struct Mol Biol 16(12):1237-43 | |
| Zhang L, et al. (2009) Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nat Struct Mol Biol 16(7):731-9 | |
| Pena V, et al. (2008) Structure and function of an RNase H domain at the heart of the spliceosome. EMBO J 27(21):2929-40 | |
| Yang K, et al. (2008) Crystal structure of the {beta}-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc Natl Acad Sci U S A 105(37):13817-22 | |
| Aronova A, et al. (2007) Functional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing. RNA 13(9):1437-44 | |
| Boon KL, et al. (2007) prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast. Nat Struct Mol Biol 14(11):1077-83 | |
| Liu L, et al. (2007) Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing. Nat Struct Mol Biol 14(6):519-26 | |
| Pleiss JA, et al. (2007) Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components. PLoS Biol 5(4):e90 | |
| Bellare P, et al. (2006) Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA 12(2):292-302 | |
| Konarska MM, et al. (2006) Repositioning of the reaction intermediate within the catalytic center of the spliceosome. Mol Cell 21(4):543-53 | |
| Tardiff DF and Rosbash M (2006) Arrested yeast splicing complexes indicate stepwise snRNP recruitment during in vivo spliceosome assembly. RNA 12(6):968-79 | |
| Turner IA, et al. (2006) Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome. RNA 12(3):375-86 | |
| Lacadie SA and Rosbash M (2005) Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast. Mol Cell 19(1):65-75 | |
| Query CC and Konarska MM (2004) Suppression of multiple substrate mutations by spliceosomal prp8 alleles suggests functional correlations with ribosomal ambiguity mutants. Mol Cell 14(3):343-54 | |
| Chawla G, et al. (2003) Dependence of pre-mRNA introns on PRP17, a non-essential splicing factor: implications for efficient progression through cell cycle transitions. Nucleic Acids Res 31(9):2333-43 | |
| McPheeters DS and Muhlenkamp P (2003) Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast. Mol Cell Biol 23(12):4174-86 | |
| Troyanskaya OG, et al. (2003) A Bayesian framework for combining heterogeneous data sources for gene function prediction (in Saccharomyces cerevisiae). Proc Natl Acad Sci U S A 100(14):8348-53 | |
| Bialkowska A and Kurlandzka A (2002) Proteins interacting with Lin 1p, a putative link between chromosome segregation, mRNA splicing and DNA replication in Saccharomyces cerevisiae. Yeast 19(15):1323-33 | |
| Kuhn AN, et al. (2002) Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activation. Proc Natl Acad Sci U S A 99(14):9145-9 | |
| Wiesner S, et al. (2002) Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40. J Mol Biol 324(4):807-22 | |
| Awasthi S, et al. (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15 | |
| Dagher SF and Fu XD (2001) Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4. RNA 7(9):1284-97 | |
| Stevens SW, et al. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7(11):1543-53 | |
| van Nues RW and Beggs JD (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157(4):1451-67 | |
| Ben-Yehuda S, et al. (2000) Extensive genetic interactions between PRP8 and PRP17/CDC40, two yeast genes involved in pre-mRNA splicing and cell cycle progression. Genetics 154(1):61-71 | |
| Ben-Yehuda S, et al. (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17 | |
| Kuhn AN and Brow DA (2000) Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Genetics 155(4):1667-82 | |
| Collins CA and Guthrie C (1999) Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome. Genes Dev 13(15):1970-82 | |
| Gottschalk A, et al. (1999) Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP. EMBO J 18(16):4535-48 | |
| Kuhn AN, et al. (1999) Splicing factor Prp8 governs U4/U6 RNA unwinding during activation of the spliceosome. Mol Cell 3(1):65-75 |




