MRC1/YCL061C Literature Guide Help

Other names published for MRC1: YCL060C, YCL061C

MRC1 - Function/Process (34)

ReferenceOther Genes Addressed
Lai MS, et al.  (2012) Rmi1 functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18-RFC complex and Mrc1. Biochem Biophys Res Commun 427(3):682-6
Zhang Y, et al.  (2012) Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell 48(2):254-65
Das-Bradoo S, et al.  (2010) Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107. Nat Cell Biol 12(1):74-9; sup pp 1-20
Kaochar S, et al.  (2010) Checkpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 107(50):21605-10
Nguyen VC, et al.  (2010) Replication stress checkpoint signaling controls tRNA gene transcription. Nat Struct Mol Biol 17(8):976-81
Randell JC, et al.  (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol Cell 40(3):353-63
Bando M, et al.  (2009) Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 284(49):34355-65
Morohashi H, et al.  (2009) The amino-terminal TPR domain of Dia2 tethers SCF(Dia2) to the replisome progression complex. Curr Biol 19(22):1943-9
Naylor ML, et al.  (2009) Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork. Proc Natl Acad Sci U S A 106(31):12765-70
Lou H, et al.  (2008) Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Mol Cell 32(1):106-17
Ohya T, et al.  (2008) A SUMO-Like Domain Protein, Esc2, Is Required for Genome Integrity and Sister Chromatid Cohesion in Saccharomyces cerevisiae. Genetics 180(1):41-50
Payen C, et al.  (2008) Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms. PLoS Genet 4(9):e1000175
Razidlo DF and Lahue RS  (2008) Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. DNA Repair (Amst) 7(4):633-40
Voineagu I, et al.  (2008) Replication stalling at unstable inverted repeats: interplay between DNA hairpins and fork stabilizing proteins. Proc Natl Acad Sci U S A 105(29):9936-41
Grandin N and Charbonneau M  (2007) Mrc1, a non-essential DNA replication protein, is required for telomere end protection following loss of capping by Cdc13, Yku or telomerase. Mol Genet Genomics 277(6):685-99
Hodgson B, et al.  (2007) Mrc1 and Tof1 Regulate DNA Replication Forks in Different Ways during Normal S Phase. Mol Biol Cell 18(10):3894-902
Tsolou A and Lydall D  (2007) Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1. DNA Repair (Amst) 6(11):1607-1617
Gambus A, et al.  (2006) GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol 8(4):358-66
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
Robert T, et al.  (2006) Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover. EMBO J 25(12):2837-46
Green BM and Li JJ  (2005) Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage. Mol Biol Cell 16(1):421-32
Szyjka SJ, et al.  (2005) Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae. Mol Cell 19(5):691-7
Tourriere H, et al.  (2005) Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53. Mol Cell 19(5):699-706
Baroni E, et al.  (2004) The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol Cell Biol 24(10):4151-65
Gibson DG, et al.  (2004) Diminished S-phase cyclin-dependent kinase function elicits vital Rad53-dependent checkpoint responses in Saccharomyces cerevisiae. Mol Cell Biol 24(23):10208-22
Lee SJ, et al.  (2004) A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation. Mol Biol Cell 15(12):5443-55
Pike BL, et al.  (2004) Rad53 kinase activation-independent replication checkpoint function of the N-terminal forkhead-associated (FHA1) domain. J Biol Chem 279(38):39636-44
Torres JZ, et al.  (2004) Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities. Mol Cell Biol 24(8):3198-212
Xu H, et al.  (2004) Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage. Mol Cell Biol 24(16):7082-90
Katou Y, et al.  (2003) S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex. Nature 424(6952):1078-83