MOT2/YER068W Literature Guide Help

Other names published for MOT2: NOT4, SIG1, CCR4-NOT core ubiquitin-protein ligase subunit MOT2, YER068W

MOT2 - Function/Process (36)

ReferenceOther Genes Addressed
Cooper KF, et al.  (2012) Oxidative-stress-induced nuclear to cytoplasmic relocalization is required for Not4-dependent cyclin C destruction. J Cell Sci 125(Pt 4):1015-26
Gulshan K, et al.  (2012) Proteolytic degradation of the Yap1 transcription factor is regulated by subcellular localization and the E3 ubiquitin ligase Not4. J Biol Chem 287(32):26796-805
Panasenko OO and Collart MA  (2012) Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase. Mol Microbiol 83(3):640-53
Assenholt J, et al.  (2011) Implication of Ccr4-Not complex function in mRNA quality control in Saccharomyces cerevisiae. RNA 17(10):1788-94
Burtner CR, et al.  (2011) A genomic analysis of chronological longevity factors in budding yeast. Cell Cycle 10(9):1385-96
Kruk JA, et al.  (2011) The multifunctional Ccr4-Not complex directly promotes transcription elongation. Genes Dev 25(6):581-93
Panasenko OO and Collart MA  (2011) Not4 E3 ligase contributes to proteasome assembly and functional integrity in part through Ecm29. Mol Cell Biol 31(8):1610-23
Haworth J, et al.  (2010) Ubc4 and Not4 Regulate Steady-State Levels of DNA Polymerase-{alpha} to Promote Efficient and Accurate DNA Replication. Mol Biol Cell 21(18):3205-19
Lee SK, et al.  (2010) Activation of a Poised RNAPII-Dependent Promoter Requires Both SAGA and Mediator. Genetics 184(3):659-72
Panasenko OO, et al.  (2009) Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitination. Genetics 181(2):447-60
Traven A, et al.  (2009) The Ccr4-Pop2-NOT mRNA Deadenylase Contributes to Septin Organization in Saccharomyces cerevisiae. Genetics 182(4):955-66
Abe F and Minegishi H  (2008) Global screening of genes essential for growth in high-pressure and cold environments: searching for basic adaptive strategies using a yeast deletion library. Genetics 178(2):851-72
Laribee RN, et al.  (2007) CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proc Natl Acad Sci U S A 104(14):5836-41
Mulder KW, et al.  (2007) Modulation of Ubc4p/Ubc5p-Mediated Stress Responses by the RING-Finger-Dependent Ubiquitin-Protein Ligase Not4p in Saccharomyces cerevisiae. Genetics 176(1):181-92
Biswas D, et al.  (2006) Genetic interactions between Nhp6 and Gcn5 with Mot1 and the Ccr4-Not complex that regulate binding of TATA-binding protein in Saccharomyces cerevisiae. Genetics 172(2):837-49
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
Guo X, et al.  (2006) Histone acetylation and transcriptional regulation in the genome of Saccharomyces cerevisiae. Bioinformatics 22(4):392-9
Hilgers V, et al.  (2006) Translation-independent inhibition of mRNA deadenylation during stress in Saccharomyces cerevisiae. RNA 12(10):1835-45
Panasenko O, et al.  (2006) The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex. J Biol Chem 281(42):31389-98
Mulder KW, et al.  (2005) DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex. Nucleic Acids Res 33(19):6384-92
Deluen C, et al.  (2002) The Ccr4-not complex and yTAF1 (yTaf(II)130p/yTaf(II)145p) show physical and functional interactions. Mol Cell Biol 22(19):6735-49
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Chen J, et al.  (2001) Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex. J Mol Biol 314(4):683-94
Denis CL, et al.  (2001) Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. Genetics 158(2):627-34
Liu HY, et al.  (2001) Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme. J Biol Chem 276(10):7541-8
Albert TK, et al.  (2000) Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits. Nucleic Acids Res 28(3):809-17
Badarinarayana V, et al.  (2000) Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155(3):1045-54
Lemaire M and Collart MA  (2000) The TATA-binding protein-associated factor yTafII19p functionally interacts with components of the global transcriptional regulator Ccr4-Not complex and physically interacts with the Not5 subunit. J Biol Chem 275(35):26925-34
Maillet L, et al.  (2000) The essential function of Not1 lies within the Ccr4-Not complex. J Mol Biol 303(2):131-43
Bai Y, et al.  (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol Cell Biol 19(10):6642-51