MGA2/YIR033W Literature Guide Help

Other names published for MGA2: YIR033W

MGA2 - Function/Process (18)

ReferenceOther Genes Addressed
Reimand J, et al.  (2012) m:Explorer - multinomial regression models reveal positive and negative regulators of longevity in yeast quiescence. Genome Biol 13(6):R55
Hickman MJ, et al.  (2011) The Hog1 mitogen-activated protein kinase mediates a hypoxic response in Saccharomyces cerevisiae. Genetics 188(2):325-38
Rice C, et al.  (2010) A role for MGA2, but not SPT23, in activation of transcription of ERG1 in Saccharomyces cerevisiae. Biochem Biophys Res Commun 403(3-4):293-7
Kaliszewski P, et al.  (2008) Rsp5p ubiquitin ligase and the transcriptional activators Spt23p and Mga2p are involved in co-regulation of biosynthesis of end products of the mevalonate pathway and triacylglycerol in yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1781(10):627-34
Guzy RD, et al.  (2007) Mitochondrial complex III is required for hypoxia-induced ROS production and gene transcription in yeast. Antioxid Redox Signal 9(9):1317-28
Oh CS and Martin CE  (2006) Candida albicans Spt23p controls the expression of the Ole1p Delta9 fatty acid desaturase and regulates unsaturated fatty acid biosynthesis. J Biol Chem 281(11):7030-9
Kandasamy P, et al.  (2004) Regulation of unsaturated fatty acid biosynthesis in Saccharomyces: the endoplasmic reticulum membrane protein, Mga2p, a transcription activator of the OLE1 gene, regulates the stability of the OLE1 mRNA through exosome-mediated mechanisms. J Biol Chem 279(35):36586-92
Lyons TJ, et al.  (2004) Metalloregulation of yeast membrane steroid receptor homologs. Proc Natl Acad Sci U S A 101(15):5506-11
Nakagawa Y, et al.  (2003) Merging of multiple signals regulating delta9 fatty acid desaturase gene transcription in Saccharomyces cerevisiae. Mol Genet Genomics 269(3):370-80
Shcherbik N, et al.  (2003) Rsp5p is required for ER bound Mga2p120 polyubiquitination and release of the processed/tethered transactivator Mga2p90. Curr Biol 13(14):1227-33
Jiang Y, et al.  (2002) Mga2p processing by hypoxia and unsaturated fatty acids in Saccharomyces cerevisiae: impact on LORE-dependent gene expression. Eukaryot Cell 1(3):481-90
Nakagawa Y, et al.  (2002) Mga2p is a putative sensor for low temperature and oxygen to induce OLE1 transcription in Saccharomyces cerevisiae. Biochem Biophys Res Commun 291(3):707-13
Chellappa R, et al.  (2001) The membrane proteins, Spt23p and Mga2p, play distinct roles in the activation of Saccharomyces cerevisiae OLE1 gene expression. Fatty acid-mediated regulation of Mga2p activity is independent of its proteolytic processing into a soluble transcription activator. J Biol Chem 276(47):43548-56
Hitchcock AL, et al.  (2001) The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol Biol Cell 12(10):3226-41
Jiang Y, et al.  (2001) MGA2 is involved in the low-oxygen response element-dependent hypoxic induction of genes in Saccharomyces cerevisiae. Mol Cell Biol 21(18):6161-9
Dula ML and Holmes SG  (2000) MGA2 and SPT23 are modifiers of transcriptional silencing in yeast. Genetics 156(3):933-41
Zhang S, et al.  (1999) MGA2 or SPT23 is required for transcription of the delta9 fatty acid desaturase gene, OLE1, and nuclear membrane integrity in Saccharomyces cerevisiae. Genetics 151(2):473-83
Zhang S, et al.  (1997) Genetic redundancy between SPT23 and MGA2: regulators of Ty-induced mutations and Ty1 transcription in Saccharomyces cerevisiae. Mol Cell Biol 17(8):4718-29