MAC1/YMR021C Literature Guide Help

Other names published for MAC1: CUA1, YMR021C

MAC1 - Function/Process (33)

ReferenceOther Genes Addressed
Liu L, et al.  (2012) Low-affinity copper transporter CTR2 is regulated by copper-sensing transcription factor Mac1p in Saccharomyces cerevisiae. Biochem Biophys Res Commun 420(3):600-4
Qi J, et al.  (2012) Metal-sensing transcription factors Mac1p and Aft1p coordinately regulate vacuolar copper transporter CTR2 in Saccharomyces cerevisiae. Biochem Biophys Res Commun 423(2):424-8
Heo DH, et al.  (2010) Cadmium regulates copper homoeostasis by inhibiting the activity of Mac1, a transcriptional activator of the copper regulon, in Saccharomyces cerevisiae. Biochem J 431(2):257-65
Laliberte J and Labbe S  (2006) Mechanisms of copper loading on the Schizosaccharomyces pombe copper amine oxidase 1 expressed in Saccharomyces cerevisiae. Microbiology 152(Pt 9):2819-30
van Bakel H, et al.  (2005) Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism. Physiol Genomics 22(3):356-67
Kyoda K, et al.  (2004) DBRF-MEGN method: an algorithm for deducing minimum equivalent gene networks from large-scale gene expression profiles of gene deletion mutants. Bioinformatics 20(16):2662-75
Marvin ME, et al.  (2004) The CaCTR1 gene is required for high-affinity iron uptake and is transcriptionally controlled by a copper-sensing transactivator encoded by CaMAC1. Microbiology 150(Pt 7):2197-208
Xiao Z, et al.  (2004) C-terminal domain of the membrane copper transporter Ctr1 from Saccharomyces cerevisiae binds four Cu(I) ions as a cuprous-thiolate polynuclear cluster: sub-femtomolar Cu(I) affinity of three proteins involved in copper trafficking. J Am Chem Soc 126(10):3081-90
Marvin ME, et al.  (2003) The Candida albicans CTR1 gene encodes a functional copper transporter. Microbiology 149(Pt 6):1461-74
Brown KR, et al.  (2002) Structures of the cuprous-thiolate clusters of the Mac1 and Ace1 transcriptional activators. Biochemistry 41(20):6469-76
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Nitiss JL  (2002) A copper connection to the uptake of platinum anticancer drugs. Proc Natl Acad Sci U S A 99(22):13963-5
Yonkovich J, et al.  (2002) Copper ion-sensing transcription factor Mac1p post-translationally controls the degradation of its target gene product Ctr1p. J Biol Chem 277(27):23981-4
Angrave FE and Avery SV  (2001) Antioxidant functions required for insusceptibility of Saccharomyces cerevisiae to tetracycline antibiotics. Antimicrob Agents Chemother 45(10):2939-42
Heredia J, et al.  (2001) Phosphorylation and Cu+ coordination-dependent DNA binding of the transcription factor Mac1p in the regulation of copper transport. J Biol Chem 276(12):8793-7
Voutsina A, et al.  (2001) The second cysteine-rich domain of Mac1p is a potent transactivator that modulates DNA binding efficiency and functionality of the protein. FEBS Lett 494(1-2):38-43
Gross C, et al.  (2000) Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays. J Biol Chem 275(41):32310-6
Keller G, et al.  (2000) Functional independence of the two cysteine-rich activation domains in the yeast Mac1 transcription factor. J Biol Chem 275(38):29193-9
Georgatsou E and Alexandraki D  (1999) Regulated expression of the Saccharomyces cerevisiae Fre1p/Fre2p Fe/Cu reductase related genes. Yeast 15(7):573-84
Jamison McDaniels CP, et al.  (1999) The yeast transcription factor Mac1 binds to DNA in a modular fashion. J Biol Chem 274(38):26962-7
Joshi A, et al.  (1999) Evidence for (Mac1p)2.DNA ternary complex formation in Mac1p-dependent transactivation at the CTR1 promoter. J Biol Chem 274(1):218-26
Serpe M, et al.  (1999) Structure-function analysis of the protein-binding domains of Mac1p, a copper-dependent transcriptional activator of copper uptake in Saccharomyces cerevisiae. J Biol Chem 274(41):29211-9
Jensen LT and Winge DR  (1998) Identification of a copper-induced intramolecular interaction in the transcription factor Mac1 from Saccharomyces cerevisiae. EMBO J 17(18):5400-8
Jensen LT, et al.  (1998) Mapping of the DNA binding domain of the copper-responsive transcription factor Mac1 from Saccharomyces cerevisiae. J Biol Chem 273(37):23805-11
Martins LJ, et al.  (1998) Metalloregulation of FRE1 and FRE2 homologs in Saccharomyces cerevisiae. J Biol Chem 273(37):23716-21
Pena MM, et al.  (1998) Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae. Mol Cell Biol 18(5):2514-23
Zhu Z, et al.  (1998) Copper differentially regulates the activity and degradation of yeast Mac1 transcription factor. J Biol Chem 273(3):1277-80
Georgatsou E, et al.  (1997) The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator. J Biol Chem 272(21):13786-92
Graden JA and Winge DR  (1997) Copper-mediated repression of the activation domain in the yeast Mac1p transcription factor. Proc Natl Acad Sci U S A 94(11):5550-5
Labbe S, et al.  (1997) Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway. J Biol Chem 272(25):15951-8