LAG1/YHL003C Literature Guide Help

Other names published for LAG1: sphingosine N-acyltransferase LAG1, YHL003C

LAG1 - Function/Process (19)

ReferenceOther Genes Addressed
Ternes P, et al.  (2011) Two Pathways of Sphingolipid Biosynthesis Are Separated in the Yeast Pichia pastoris. J Biol Chem 286(13):11401-14
Dawaliby R and Mayer A  (2010) Microautophagy of the nucleus coincides with a vacuolar diffusion barrier at nuclear-vacuolar junctions. Mol Biol Cell 21(23):4173-83
Guan XL, et al.  (2010) Yeast lipid analysis and quantification by mass spectrometry. Methods Enzymol 470():369-91
Cerantola V, et al.  (2007) Yeast sphingolipids do not need to contain very long chain fatty acids. Biochem J 401(1):205-216
Vallee B and Riezman H  (2005) Lip1p: a novel subunit of acyl-CoA ceramide synthase. EMBO J 24(4):730-41
Jiang JC, et al.  (2004) Suppressor analysis points to the subtle role of the LAG1 ceramide synthase gene in determining yeast longevity. Exp Gerontol 39(7):999-1009
Kolaczkowski M, et al.  (2004) Differential regulation of ceramide synthase components LAC1 and LAG1 in Saccharomyces cerevisiae. Eukaryot Cell 3(4):880-92
Guillas I, et al.  (2003) Human homologues of LAG1 reconstitute Acyl-CoA-dependent ceramide synthesis in yeast. J Biol Chem 278(39):37083-91
Jazwinski SM and Conzelmann A  (2002) LAG1 puts the focus on ceramide signaling. Int J Biochem Cell Biol 34(11):1491-5
Venkataraman K and Futerman AH  (2002) Do longevity assurance genes containing Hox domains regulate cell development via ceramide synthesis? FEBS Lett 528(1-3):3-4
Venkataraman K, et al.  (2002) Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. J Biol Chem 277(38):35642-9
Guillas I, et al.  (2001) C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p. EMBO J 20(11):2655-65
Pan H, et al.  (2001) Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1. Genomics 77(1-2):58-64
Schorling S, et al.  (2001) Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae. Mol Biol Cell 12(11):3417-27
Brandwagt BF, et al.  (2000) A longevity assurance gene homolog of tomato mediates resistance to Alternaria alternata f. sp. lycopersici toxins and fumonisin B1. Proc Natl Acad Sci U S A 97(9):4961-6
Barz WP and Walter P  (1999) Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol-anchored proteins. Mol Biol Cell 10(4):1043-59
Jiang JC, et al.  (1998) Homologs of the yeast longevity gene LAG1 in Caenorhabditis elegans and human. Genome Res 8(12):1259-72
Sinclair D, et al.  (1998) Aging in Saccharomyces cerevisiae. Annu Rev Microbiol 52:533-60
D'mello NP, et al.  (1994) Cloning and characterization of LAG1, a longevity-assurance gene in yeast. J Biol Chem 269(22):15451-9