IME2/YJL106W Literature Guide Help

Other names published for IME2: SME1, YJL106W

IME2 - Function/Process (40)

ReferenceOther Genes Addressed
Brush GS, et al.  (2012) Yeast IME2 Functions Early in Meiosis Upstream of Cell Cycle-Regulated SBF and MBF Targets. PLoS One 7(2):e31575
Strudwick N, et al.  (2010) Ime1 and Ime2 Are Required for Pseudohyphal Growth of Saccharomyces cerevisiae on Nonfermentable Carbon Sources. Mol Cell Biol 30(23):5514-30
Szwarcwort-Cohen M, et al.  (2010) Ectopic expression of human Cdk2 and its yeast homolog, Ime2, is deleterious to Saccharomyces cerevisiae. Cell Cycle 9(23):4711-9
Ahmed NT, et al.  (2009) The Ime2 protein kinase enhances the disassociation of the Sum1 repressor from middle meiotic promoters. Mol Cell Biol 29(16):4352-62
McDonald CM, et al.  (2009) The Ras/cAMP Pathway and the CDK-Like Kinase Ime2 Regulate the MAPK Smk1 and Spore Morphogenesis in Saccharomyces cerevisiae. Genetics 181(2):511-23
Holt LJ, et al.  (2007) Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis. Mol Cell 25(5):689-702
Sawarynski KE, et al.  (2007) Distinct activities of the related protein kinases Cdk1 and Ime2. Biochim Biophys Acta 1773(3):450-6
Schindler K and Winter E  (2006) Phosphorylation of Ime2 regulates meiotic progression in Saccharomyces cerevisiae. J Biol Chem 281(27):18307-16
Sedgwick C, et al.  (2006) Saccharomyces cerevisiae Ime2 phosphorylates Sic1 at multiple PXS/T sites but is insufficient to trigger Sic1 degradation. Biochem J 399(1):151-60
Clifford DM, et al.  (2005) Mechanistic insight into the Cdc28-related protein kinase Ime2 through analysis of replication protein A phosphorylation. Cell Cycle 4(12):1826-33
Ptacek J, et al.  (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84
Purnapatre K, et al.  (2005) Glucose inhibits meiotic DNA replication through SCFGrr1p-dependent destruction of Ime2p kinase. Mol Cell Biol 25(1):440-50
Clifford DM, et al.  (2004) The meiosis-specific protein kinase Ime2 directs phosphorylation of replication protein A. J Biol Chem 279(7):6163-70
Benjamin KR, et al.  (2003) Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2. Genes Dev 17(12):1524-39
Schindler K, et al.  (2003) The Cdk-activating kinase Cak1p promotes meiotic S phase through Ime2p. Mol Cell Biol 23(23):8718-28
Shubassi G, et al.  (2003) Activity of phosphoforms and truncated versions of Ndt80, a checkpoint-regulated sporulation-specific transcription factor of Saccharomyces cerevisiae. Mol Genet Genomics 270(4):324-36
Bolte M, et al.  (2002) Inhibition of APC-mediated proteolysis by the meiosis-specific protein kinase Ime2. Proc Natl Acad Sci U S A 99(7):4385-90
Pak J and Segall J  (2002) Regulation of the premiddle and middle phases of expression of the NDT80 gene during sporulation of Saccharomyces cerevisiae. Mol Cell Biol 22(18):6417-29
Sopko R, et al.  (2002) Phosphorylation and maximal activity of Saccharomyces cerevisiae meiosis-specific transcription factor Ndt80 is dependent on Ime2. Mol Cell Biol 22(20):7024-40
Deng C and Saunders WS  (2001) RIM4 encodes a meiotic activator required for early events of meiosis in Saccharomyces cerevisiae. Mol Genet Genomics 266(3):497-504
Guttmann-Raviv N, et al.  (2001) Cdc28 and Ime2 possess redundant functions in promoting entry into premeiotic DNA replication in Saccharomyces cerevisiae. Genetics 159(4):1547-58
Pijnappel WW, et al.  (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 15(22):2991-3004
Ohkuni K and Yamashita I  (2000) A transcriptional autoregulatory loop for KIN28-CCL1 and SRB10-SRB11, each encoding RNA polymerase II CTD kinase-cyclin pair, stimulates the meiotic development of S. cerevisiae. Yeast 16(9):829-46
Soushko M and Mitchell AP  (2000) An RNA-binding protein homologue that promotes sporulation-specific gene expression in Saccharomyces cerevisiae. Yeast 16(7):631-9
Zhu H, et al.  (2000) Analysis of yeast protein kinases using protein chips. Nat Genet 26(3):283-9
Burgess SM, et al.  (1999) GCN5-dependent histone H3 acetylation and RPD3-dependent histone H4 deacetylation have distinct, opposing effects on IME2 transcription, during meiosis and during vegetative growth, in budding yeast. Proc Natl Acad Sci U S A 96(12):6835-40
Donzeau M and Bandlow W  (1999) The yeast trimeric guanine nucleotide-binding protein alpha subunit, Gpa2p, controls the meiosis-specific kinase Ime2p activity in response to nutrients. Mol Cell Biol 19(9):6110-9
Yukawa M, et al.  (1999) Nps1/Sth1p, a component of an essential chromatin-remodeling complex of Saccharomyces cerevisiae, is required for the maximal expression of early meiotic genes. Genes Cells 4(2):99-110
Dirick L, et al.  (1998) Regulation of meiotic S phase by Ime2 and a Clb5,6-associated kinase in Saccharomyces cerevisiae. Science 281(5384):1854-7
Hayashi M, et al.  (1998) An extracellular meiosis-promoting factor in Saccharomyces cerevisiae. Yeast 14(7):617-22