HPR1/YDR138W Literature Guide Help

Other names published for HPR1: TRF1, YDR138W

HPR1 - Function/Process (40)

ReferenceOther Genes Addressed
Pereira FB, et al.  (2011) Identification of candidate genes for yeast engineering to improve bioethanol production in Very-High-Gravity and lignocellulosic biomass industrial fermentations. Biotechnol Biofuels 4(1):57
Gomez-Gonzalez B, et al.  (2009) The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants. Mol Cell Biol 29(19):5203-13
Qu X, et al.  (2009) Assembly of an export-competent mRNP is needed for efficient release of the 3'-end processing complex after polyadenylation. Mol Cell Biol 29(19):5327-38
Garcia-Rubio M, et al.  (2008) Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity. Mol Genet Genomics 279(2):123-32
Gonzalez-Aguilera C, et al.  (2008) The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability. Mol Biol Cell 19(10):4310-8
Rougemaille M, et al.  (2008) THO/Sub2p functions to coordinate 3'-end processing with gene-nuclear pore association. Cell 135(2):308-21
Saguez C, et al.  (2008) Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation. Mol Cell 31(1):91-103
Gaillard H, et al.  (2007) A new connection of mRNP biogenesis and export with transcription-coupled repair. Nucleic Acids Res 35(12):3893-906
Huertas P, et al.  (2006) An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination. Mol Cell Biol 26(20):7451-65
Gwizdek C, et al.  (2005) The mRNA nuclear export factor Hpr1 is regulated by Rsp5-mediated ubiquitylation. J Biol Chem 280(14):13401-5
Mason PB and Struhl K  (2005) Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo. Mol Cell 17(6):831-40
Freedman JA and Jinks-Robertson S  (2004) Effects of mismatch repair and Hpr1 on transcription-stimulated mitotic recombination in the yeast Saccharomyces cerevisiae. DNA Repair (Amst) 3(11):1437-46
Hacker S and Krebber H  (2004) Differential export requirements for shuttling serine/arginine-type mRNA-binding proteins. J Biol Chem 279(7):5049-52
Huertas P and Aguilera A  (2003) Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol Cell 12(3):711-21
Rondon AG, et al.  (2003) Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation. J Biol Chem 278(40):39037-43
Betz JL, et al.  (2002) Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Mol Genet Genomics 268(2):272-85
Gonzalez-Barrera S, et al.  (2002) Defective nucleotide excision repair in yeast hpr1 and tho2 mutants. Nucleic Acids Res 30(10):2193-201
Jimeno S, et al.  (2002) The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability. EMBO J 21(13):3526-35
Libri D, et al.  (2002) Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation. Mol Cell Biol 22(23):8254-66
Merker RJ and Klein HL  (2002) Role of transcription in plasmid maintenance in the hpr1Delta mutant of Saccharomyces cerevisiae. Mol Cell Biol 22(24):8763-73
Merker RJ and Klein HL  (2002) hpr1Delta affects ribosomal DNA recombination and cell life span in Saccharomyces cerevisiae. Mol Cell Biol 22(2):421-9
Porter SE, et al.  (2002) The yeast pafl-rNA polymerase II complex is required for full expression of a subset of cell cycle-regulated genes. Eukaryot Cell 1(5):830-42
Strasser K, et al.  (2002) TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417(6886):304-8
Zenklusen D, et al.  (2002) Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p. Mol Cell Biol 22(23):8241-53
Chavez S, et al.  (2001) Hpr1 is preferentially required for transcription of either long or G+C-rich DNA sequences in Saccharomyces cerevisiae. Mol Cell Biol 21(20):7054-64
Fan HY, et al.  (2001) High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability. Mol Cell Biol 21(16):5459-70
Gallardo M and Aguilera A  (2001) A new hyperrecombination mutation identifies a novel yeast gene, THP1, connecting transcription elongation with mitotic recombination. Genetics 157(1):79-89
Chang M, et al.  (1999) A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling. Mol Cell Biol 19(2):1056-67
Piruat JI and Aguilera A  (1998) A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination. EMBO J 17(16):4859-72
Chavez S and Aguilera A  (1997) The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability. Genes Dev 11(24):3459-70