DNL4/YOR005C Literature Guide Help

Other names published for DNL4: LIG4, DNA ligase (ATP) DNL4, YOR005C

DNL4 - Function/Process (36)

ReferenceOther Genes Addressed
Chaurasia P, et al.  (2012) Preferential repair of DNA double-strand break at the active gene in vivo. J Biol Chem 287(43):36414-22
Chen X and Tomkinson AE  (2011) Yeast nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining. J Biol Chem 286(6):4931-40
Fritsch O, et al.  (2010) DNA ligase 4 stabilizes the ribosomal DNA array upon fork collapse at the replication fork barrier. DNA Repair (Amst) 9(8):879-888
Sundararajan R, et al.  (2010) Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiae. Genetics 184(1):65-77
Fung CW, et al.  (2009) Suppression of the Double-Strand-Break-Repair Defect of the Saccharomyces cerevisiae rad57 Mutant. Genetics 181(4):1195-206
Pike JE, et al.  (2009) Pif1 Helicase Lengthens Some Okazaki Fragment Flaps Necessitating Dna2 Nuclease/Helicase Action in the Two-nuclease Processing Pathway. J Biol Chem 284(37):25170-80
Clerici M, et al.  (2008) The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle. EMBO Rep 9(8):810-8
Lee K, et al.  (2008) Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations. Nature 454(7203):543-6
Meyer DH and Bailis AM  (2008) Mating type influences chromosome loss and replicative senescence in telomerase-deficient budding yeast by Dnl4-dependent telomere fusion. Mol Microbiol 69(5):1246-54
Pannunzio NR, et al.  (2008) RAD59 is required for efficient repair of simultaneous double-strand breaks resulting in translocations in Saccharomyces cerevisiae. DNA Repair (Amst) 7(5):788-800
Payen C, et al.  (2008) Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms. PLoS Genet 4(9):e1000175
Zhang Y, et al.  (2007) Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination. Nat Struct Mol Biol 14(7):639-46
Barber LJ, et al.  (2005) DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase. Mol Cell Biol 25(6):2297-309
Clatworthy AE, et al.  (2005) The MRE11-RAD50-XRS2 complex, in addition to other non-homologous end-joining factors, is required for V(D)J joining in yeast. J Biol Chem 280(21):20247-52
Pardo B and Marcand S  (2005) Rap1 prevents telomere fusions by nonhomologous end joining. EMBO J 24(17):3117-27
Tseng HM and Tomkinson AE  (2004) Processing and joining of DNA ends coordinated by interactions among Dnl4/Lif1, Pol4, and FEN-1. J Biol Chem 279(46):47580-8
Wang X, et al.  (2004) Role of DNA replication proteins in double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol 24(16):6891-9
Heidenreich E, et al.  (2003) Non-homologous end joining as an important mutagenic process in cell cycle-arrested cells. EMBO J 22(9):2274-83
Liti G and Louis EJ  (2003) NEJ1 prevents NHEJ-dependent telomere fusions in yeast without telomerase. Mol Cell 11(5):1373-8
Ma JL, et al.  (2003) Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences. Mol Cell Biol 23(23):8820-8
Mieczkowski PA, et al.  (2003) Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae. Proc Natl Acad Sci U S A 100(19):10854-9
Van Attikum H and Hooykaas PJ  (2003) Genetic requirements for the targeted integration of Agrobacterium T-DNA in Saccharomyces cerevisiae. Nucleic Acids Res 31(3):826-32
Frank-Vaillant M and Marcand S  (2002) Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination. Mol Cell 10(5):1189-99
Tseng HM and Tomkinson AE  (2002) A physical and functional interaction between yeast Pol4 and Dnl4-Lif1 links DNA synthesis and ligation in nonhomologous end joining. J Biol Chem 277(47):45630-7
Wilson TE  (2002) A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio. Genetics 162(2):677-88
Chen L, et al.  (2001) Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol Cell 8(5):1105-15
Donahue SL, et al.  (2001) Mitochondrial DNA ligase function in Saccharomyces cerevisiae. Nucleic Acids Res 29(7):1582-9
Frank-Vaillant M and Marcand S  (2001) NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway. Genes Dev 15(22):3005-12
van Attikum H, et al.  (2001) Non-homologous end-joining proteins are required for Agrobacterium T-DNA integration. EMBO J 20(22):6550-8
Teo SH and Jackson SP  (2000) Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks. Curr Biol 10(3):165-8