DBF4/YDR052C Literature Guide Help

Other names published for DBF4: LSD7, DNA52, YDR052C

DBF4 - Function/Process (32)

ReferenceOther Genes Addressed
Baker SP, et al.  (2010) Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae. Nat Cell Biol 12(3):294-8
Jones DR, et al.  (2010) The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress. Cell Cycle 9(10):2018-26
Zegerman P and Diffley JF  (2010) Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation. Nature 467(7314):474-8
Bruck I and Kaplan D  (2009) Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth. J Biol Chem 284(42):28823-31
Harkins V, et al.  (2009) Budding yeast Dbf4 sequences required for Cdc7 kinase activation and identification of a functional relationship between the Dbf4 and Rev1 BRCT domains. Genetics 183(4):1269-82
Miller CT, et al.  (2009) Cdc7p-dbf4p regulates mitotic exit by inhibiting polo kinase. PLoS Genet 5(5):e1000498
Ogi H, et al.  (2008) The role of the Saccharomyces cerevisiae Cdc7-Dbf4 complex in the replication checkpoint. Gene 414(1-2):32-40
Sullivan M, et al.  (2008) Cyclin-specific control of ribosomal DNA segregation. Mol Cell Biol 28(17):5328-36
Wan L, et al.  (2008) Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast. Genes Dev 22(3):386-97
Hoang ML, et al.  (2007) Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae. Mol Cell Biol 27(21):7594-602
Sheu YJ and Stillman B  (2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell 24(1):101-13
Valentin G, et al.  (2006) Dual role of the Cdc7-regulatory protein Dbf4 during yeast meiosis. J Biol Chem 281(5):2828-34
Yu L, et al.  (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47
Pessoa-Brandao L and Sclafani RA  (2004) CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae. Genetics 167(4):1597-610
Sclafani RA, et al.  (2002) The mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae. Genetics 161(1):47-57
Ferreira MF, et al.  (2000) Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex. Mol Cell Biol 20(1):242-8
Kihara M, et al.  (2000) Characterization of the yeast Cdc7p/Dbf4p complex purified from insect cells. Its protein kinase activity is regulated by Rad53p. J Biol Chem 275(45):35051-62
Nakamura T, et al.  (2000) The Schizosaccharomyces pombe spo6+ gene encoding a nuclear protein with sequence similarity to budding yeast Dbf4 is required for meiotic second division and sporulation. Genes Cells 5(6):463-79
Nougarede R, et al.  (2000) Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation. Mol Cell Biol 20(11):3795-806
Sclafani RA  (2000) Cdc7p-Dbf4p becomes famous in the cell cycle. J Cell Sci 113 ( Pt 12):2111-7
Zhu H, et al.  (2000) Analysis of yeast protein kinases using protein chips. Nat Genet 26(3):283-9
Cheng L, et al.  (1999) Cell cycle regulation of DNA replication initiator factor Dbf4p. Mol Cell Biol 19(6):4270-8
Costanzo V, et al.  (1999) Protein kinase A is required for chromosomal DNA replication. Curr Biol 9(16):903-6
Lepke M, et al.  (1999) Identification, characterization and chromosomal localization of the cognate human and murine DBF4 genes. Mol Gen Genet 262(2):220-9
Oshiro G, et al.  (1999) Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability. Mol Cell Biol 19(7):4888-96
Pasero P, et al.  (1999) A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication. Genes Dev 13(16):2159-76
Wang H and Elledge SJ  (1999) DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(7):3824-9
Weinreich M and Stillman B  (1999) Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway. EMBO J 18(19):5334-46
Tanaka T and Nasmyth K  (1998) Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases. EMBO J 17(17):5182-91
Lei M, et al.  (1997) Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis. Genes Dev 11(24):3365-74