COX2/Q0250 Literature Guide Help

Other names published for COX2: OXI1, OXII, cytochrome c oxidase subunit 2, Q0250

COX2 - Function/Process (28)

ReferenceOther Genes Addressed
Cruz-Torres V, et al.  (2012) The cytosol-synthesized subunit II (Cox2) precursor with the point mutation W56R is correctly processed in yeast mitochondria to rescue cytochrome oxidase. Biochim Biophys Acta 1817(12):2128-39
Trouillard M, et al.  (2011) Questioning the functional relevance of mitochondrial supercomplexes by time-resolved analysis of the respiratory chain. Proc Natl Acad Sci U S A 108(45):E1027-34
Zuo X, et al.  (2011) Miltefosine induces apoptosis-like cell death in yeast via Cox9p in cytochrome c oxidase. Mol Pharmacol 80(3):476-85
Perez-Martinez X, et al.  (2009) Dual Functions of Mss51 Couple Synthesis of Cox1 to Assembly of Cytochrome c Oxidase in Saccharomyces cerevisiae Mitochondria. Mol Biol Cell 20(20):4371-80
Herst PM, et al.  (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
Castello PR, et al.  (2006) Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signaling in eukaryotes. Cell Metab 3(4):277-87
David PS and Poyton RO  (2005) Effects of a transition from normoxia to anoxia on yeast cytochrome c oxidase and the mitochondrial respiratory chain: implications for hypoxic gene induction. Biochim Biophys Acta 1709(2):169-80
Horan S, et al.  (2005) Analysis of COX2 mutants reveals cytochrome oxidase subassemblies in yeast. Biochem J 390(Pt 3):703-8
Xu N, et al.  (2005) Mitochondrial DNA impacts the morphology of mitochondrial compartments. Gene 354:37-42
Herrmann JM and Bonnefoy N  (2004) Protein export across the inner membrane of mitochondria: the nature of translocated domains determines the dependence on the Oxa1 translocase. J Biol Chem 279(4):2507-12
Bonnefoy N, et al.  (2001) Mitochondrial translation of Saccharomyces cerevisiae COX2 mRNA is controlled by the nucleotide sequence specifying the pre-Cox2p leader peptide. Mol Cell Biol 21(7):2359-72
Broadley SA, et al.  (2001) Peripheral mitochondrial inner membrane protein, Mss2p, required for export of the mitochondrially coded Cox2p C tail in Saccharomyces cerevisiae. Mol Cell Biol 21(22):7663-72
Machingo Q, et al.  (2001) Second-site, intragenic alterations in the gene encoding subunit II of cytochrome c oxidase from yeast can suppress two different missense mutations. Curr Genet 39(5-6):297-304
Dickinson EK, et al.  (2000) A human SCO2 mutation helps define the role of Sco1p in the cytochrome oxidase assembly pathway. J Biol Chem 275(35):26780-5
Hell K, et al.  (2000) Identification of Cox20p, a novel protein involved in the maturation and assembly of cytochrome oxidase subunit 2. J Biol Chem 275(7):4571-8
Souza RL, et al.  (2000) Cloning and characterization of COX18, a Saccharomyces cerevisiae PET gene required for the assembly of cytochrome oxidase. J Biol Chem 275(20):14898-902
Mazourek M, et al.  (1999) Analysis of strains of Saccharomyces cerevisiae with amino acid substitutions in the Cu(A)-binding region of subunit II of cytochrome c oxidase. Curr Genet 36(5):249-55
Lemaire C, et al.  (1998) Molecular and biochemical analysis of Saccharomyces cerevisiae cox1 mutants. Curr Genet 34(2):138-45
Overholtzer MH, et al.  (1996) The effect of amino acid substitutions in the conserved aromatic region of subunit II of cytochrome c oxidase in Saccharomyces cerevisiae. J Biol Chem 271(13):7719-24
Taanman JW and Capaldi RA  (1992) Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme. J Biol Chem 267(31):22481-5
George-Nascimento C and Poyton RO  (1981) Further analysis of the polypeptide subunits of yeast cytochrome c oxidase. Isolation and characterization of subunits III, V, and VII. J Biol Chem 256(17):9363-70
Azzi A and Casey RP  (1979) Molecular aspects of cytochrome c oxidase: structure and dynamics. Mol Cell Biochem 28(1-3):169-84
Cabral F and Schatz G  (1978) Identification of cytochrome c oxidase subunits in nuclear yeast mutants lacking the functional enzyme. J Biol Chem 253(12):4396-401
Poyton RO, et al.  (1978) The use of orthacryl two-dimensional polyacrylamide gel electrophoresis to identify and compare the subunit polypeptides of bovine heart and yeast cytochrome c oxidases. J Biol Chem 253(18):6303-6
Eytan GD and Schatz G  (1975) Cytochrome c oxidase from bakers' yeast. V. Arrangement of the subunits in the isolated and membrane-bound enzyme. J Biol Chem 250(2):767-74
Poyton RO and Schatz G  (1975) Cytochrome c oxidase from bakers' yeast. III. Physical characterization of isolated subunits and chemical evidence for two different classes of polypeptides. J Biol Chem 250(2):752-61
Poyton RO and Schatz G  (1975) Cytochrome c oxidase from bakers' yeast. IV. Immunological evidence for the participation of a mitochondrially synthesized subunit in enzymatic activity. J Biol Chem 250(2):762-6
Ebner E and Schatz G  (1973) Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. 3. A nuclear mutant lacking mitochondrial adenosine triphosphatase. J Biol Chem 248(15):5379-84