CHK1/YBR274W Literature Guide Help

Other names published for CHK1: YBR274W

CHK1 - Function/Process (32)

ReferenceOther Genes Addressed
Kaochar S, et al.  (2010) Checkpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 107(50):21605-10
Pereira E, et al.  (2009) Conserved ATRMec1 phosphorylation-independent activation of Chk1 by single amino acid substitution in the GD domain. Cell Cycle 8(11):1788-93
Caldwell JM, et al.  (2008) Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins. J Cell Biol 180(6):1073-86
Lee K, et al.  (2008) Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations. Nature 454(7203):543-6
Razidlo DF and Lahue RS  (2008) Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. DNA Repair (Amst) 7(4):633-40
Bracesco N, et al.  (2007) Roles of Saccharomyces cerevisiae RAD17 and CHK1 checkpoint genes in the repair of double-strand breaks in cycling cells. Radiat Environ Biophys 46(4):401-7
Liang F and Wang Y  (2007) DNA damage checkpoints inhibit mitotic exit by two different mechanisms. Mol Cell Biol 27(14):5067-78
Fasullo M, et al.  (2005) Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents. DNA Repair (Amst) 4(11):1240-51
Michelson RJ, et al.  (2005) A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint. Genes Dev 19(21):2546-59
Baroni E, et al.  (2004) The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol Cell Biol 24(10):4151-65
Blankley RT and Lydall D  (2004) A domain of Rad9 specifically required for activation of Chk1 in budding yeast. J Cell Sci 117(Pt 4):601-8
Clerici M, et al.  (2004) A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1. Mol Cell Biol 24(23):10126-44
Haghnazari E and Heyer WD  (2004) The DNA damage checkpoint pathways exert multiple controls on the efficiency and outcome of the repair of a double-stranded DNA gap. Nucleic Acids Res 32(14):4257-68
Jia X, et al.  (2004) Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants. Genetics 166(2):753-64
Lahiri M, et al.  (2004) Expanded CAG repeats activate the DNA damage checkpoint pathway. Mol Cell 15(2):287-93
Searle JS, et al.  (2004) The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression. Nat Cell Biol 6(2):138-45
Agarwal R, et al.  (2003) Two distinct pathways for inhibiting pds1 ubiquitination in response to DNA damage. J Biol Chem 278(45):45027-33
Kaplun L, et al.  (2003) DNA damage response-mediated degradation of Ho endonuclease via the ubiquitin system involves its nuclear export. J Biol Chem 278(49):48727-34
Krylov DM, et al.  (2003) Evolution of eukaryotic cell cycle regulation: stepwise addition of regulatory kinases and late advent of the CDKs. Curr Biol 13(2):173-7
Kim EM, et al.  (2002) Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res 30(3):643-8
Maringele L and Lydall D  (2002) EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev 16(15):1919-33
Schwartz MF, et al.  (2002) Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Mol Cell 9(5):1055-65
Alcasabas AA, et al.  (2001) Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat Cell Biol 3(11):958-65
Clarke DJ, et al.  (2001) Mec1p regulates Pds1p levels in S phase: complex coordination of DNA replication and mitosis. Nat Cell Biol 3(7):619-27
Grenon M, et al.  (2001) Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex. Nat Cell Biol 3(9):844-7
Jones S and Sgouros J  (2001) The cohesin complex: sequence homologies, interaction networks and shared motifs. Genome Biol 2(3):RESEARCH0009
Myung K, et al.  (2001) Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 104(3):397-408
Wang H, et al.  (2001) Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function. Genes Dev 15(11):1361-72
Craven RJ and Petes TD  (2000) Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae. Mol Cell Biol 20(7):2378-84
Liu Y, et al.  (2000) Characterization of a Saccharomyces cerevisiae homologue of Schizosaccharomyces pombe Chk1 involved in DNA-damage-induced M-phase arrest. Mol Gen Genet 262(6):1132-46