CDC4/YFL009W Literature Guide Help

Other names published for CDC4: SCF ubiquitin ligase complex subunit CDC4, YFL009W

CDC4 - Function/Process (78)

ReferenceOther Genes Addressed
Amin AD, et al.  (2012) The mitotic Clb cyclins are required to alleviate HIR-mediated repression of the yeast histone genes at the G1/S transition. Biochim Biophys Acta 1819(1):16-27
Lass A, et al.  (2011) The loop-less tmCdc34 E2 mutant defective in polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2. Cell Div 6(1):7
Liu Q, et al.  (2011) SCFCdc4 Enables Mating Type Switching in Yeast by Cyclin-Dependent Kinase-Mediated Elimination of the Ash1 Transcriptional Repressor. Mol Cell Biol 31(3):584-98
Tumusiime S, et al.  (2011) Differential regulation of transcription factors Stp1 and Stp2 in the Ssy1-Ptr3-Ssy5 amino acid sensing pathway. J Biol Chem 286(6):4620-31
Bao MZ, et al.  (2010) Multisite phosphorylation of the Saccharomyces cerevisiae filamentous growth regulator Tec1 is required for its recognition by the E3 ubiquitin ligase adaptor Cdc4 and its subsequent destruction in vivo. Eukaryot Cell 9(1):31-6
Cappell SD, et al.  (2010) Systematic analysis of essential genes reveals important regulators of G protein signaling. Mol Cell 38(5):746-57
Orlicky S, et al.  (2010) An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase. Nat Biotechnol 28(7):733-7
Garrenton LS, et al.  (2009) Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence. Mol Cell Biol 29(2):582-601
Escamilla-Powers JR and Sears RC  (2007) A conserved pathway that controls c-Myc protein stability through opposing phosphorylation events occurs in yeast. J Biol Chem 282(8):5432-42
Yu L, et al.  (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47
Petroski MD and Deshaies RJ  (2005) Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34. Cell 123(6):1107-20
Shieh JC, et al.  (2005) Identification and functional characterization of Candida albicans CDC4. J Biomed Sci 12(6):913-24
Chou S, et al.  (2004) Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast. Cell 119(7):981-90
Kus BM, et al.  (2004) Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro. Proteins 54(3):455-67
Deffenbaugh AE, et al.  (2003) Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1. Cell 114(5):611-22
Dixon C, et al.  (2003) Overproduction of polypeptides corresponding to the amino terminus of the F-box proteins Cdc4p and Met30p inhibits ubiquitin ligase activities of their SCF complexes. Eukaryot Cell 2(1):123-33
Orlicky S, et al.  (2003) Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase. Cell 112(2):243-56
Petroski MD and Deshaies RJ  (2003) Context of multiubiquitin chain attachment influences the rate of Sic1 degradation. Mol Cell 11(6):1435-44
Cui Z, et al.  (2002) Cdc4 is involved in the transcriptional control of OCH1, a gene encoding alpha-1,6-mannosyltransferase in Saccharomyces cerevisiae. Yeast 19(1):69-77
Chi Y, et al.  (2001) Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev 15(9):1078-92
Huang JN, et al.  (2001) Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p. J Cell Biol 154(1):85-94
Jager S, et al.  (2001) Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4. EMBO J 20(16):4423-31
Mizunuma M, et al.  (2001) GSK-3 kinase Mck1 and calcineurin coordinately mediate Hsl1 down-regulation by Ca2+ in budding yeast. EMBO J 20(5):1074-85
Nash P, et al.  (2001) Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature 414(6863):514-21
Perkins G, et al.  (2001) Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis. EMBO J 20(17):4836-45
Blondel M, et al.  (2000) Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in saccharomyces cerevisiae. Genetics 155(3):1033-44
Blondel M, et al.  (2000) Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4. EMBO J 19(22):6085-97
Drury LS, et al.  (2000) The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle. Curr Biol 10(5):231-40
Kaiser P, et al.  (2000) Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4. Cell 102(3):303-14
Meimoun A, et al.  (2000) Degradation of the transcription factor Gcn4 requires the kinase Pho85 and the SCF(CDC4) ubiquitin-ligase complex. Mol Biol Cell 11(3):915-27