ATG12/YBR217W Literature Guide Help

Other names published for ATG12: APG12, YBR217W

ATG12 - Function/Process (27)

ReferenceOther Genes Addressed
Piggott N, et al.  (2011) Genome-wide Fitness Profiles Reveal a Requirement for Autophagy During Yeast Fermentation. G3 (Bethesda) 1(5):353-67
Kanki T, et al.  (2009) A genomic screen for yeast mutants defective in selective mitochondria autophagy. Mol Biol Cell 20(22):4730-8
Cao Y and Klionsky DJ  (2008) New insights into autophagy using a multiple knockout strain. Autophagy 4(8):1073-5
Cao Y, et al.  (2008) In vivo reconstitution of autophagy in Saccharomyces cerevisiae. J Cell Biol 182(4):703-13
Krick R, et al.  (2008) Piecemeal microautophagy of the nucleus requires the core macroautophagy genes. Mol Biol Cell 19(10):4492-505
Hanada T, et al.  (2007) The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy. J Biol Chem 282(52):37298-302
Suzuki K, et al.  (2007) Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 12(2):209-18
Zhang Y, et al.  (2007) The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains. Autophagy 3(4):337-46
Hanada T and Ohsumi Y  (2005) Structure-function relationship of Atg12, a ubiquitin-like modifier essential for autophagy. Autophagy 1(2):110-8
Mizushima N, et al.  (2003) Role of the Apg12 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 35(5):553-61
Yamazaki-Sato H, et al.  (2003) The carboxyl terminal 17 amino acids within Apg7 are essential for Apg8 lipidation, but not for Apg12 conjugation. FEBS Lett 551(1-3):71-7
Kuma A, et al.  (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277(21):18619-25
Mizushima N, et al.  (2002) Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method. FEBS Lett 532(3):450-4
Kim J, et al.  (2001) Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex. J Cell Biol 152(1):51-64
Komatsu M, et al.  (2001) The C-terminal region of an Apg7p/Cvt2p is required for homodimerization and is essential for its E1 activity and E1-E2 complex formation. J Biol Chem 276(13):9846-54
Ohsumi Y  (2001) [Molecular mechanism of bulk protein degradation in lysosome/vacuole] Tanpakushitsu Kakusan Koso 46(11 Suppl):1710-6
Suzuki K, et al.  (2001) The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J 20(21):5971-81
Furukawa K, et al.  (2000) A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes. J Biol Chem 275(11):7462-5
George MD, et al.  (2000) Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways. Mol Biol Cell 11(3):969-82
Kim J, et al.  (1999) Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways. Mol Biol Cell 10(5):1337-51
Mizushima N, et al.  (1999) Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway. EMBO J 18(14):3888-96
Shintani T, et al.  (1999) Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast. EMBO J 18(19):5234-41
Tanida I, et al.  (1999) Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. Mol Biol Cell 10(5):1367-79
Jentsch S and Ulrich HD  (1998) Protein breakdown. Ubiquitous deja vu. Nature 395(6700):321, 323
Mizushima N, et al.  (1998) A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy. J Biol Chem 273(51):33889-92
Mizushima N, et al.  (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8
Tsukada M and Ohsumi Y  (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74