TLC1 Literature Guide Help

Other names published for TLC1: TER1

TLC1 - Function/Process (61)

ReferenceOther Genes Addressed
IJpma AS and Greider CW  (2003) Short telomeres induce a DNA damage response in Saccharomyces cerevisiae. Mol Biol Cell 14(3):987-1001
Lowell JE, et al.  (2003) Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae. Genetics 164(3):909-21
Stellwagen AE, et al.  (2003) Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev 17(19):2384-95
Taggart AK and Zakian VA  (2003) Telomerase: what are the Est proteins doing? Curr Opin Cell Biol 15(3):275-80
Tsukamoto M, et al.  (2003) The N-terminal DNA-binding domain of Rad52 promotes RAD51-independent recombination in Saccharomyces cerevisiae. Genetics 165(4):1703-15
Ferrezuelo F, et al.  (2002) Biogenesis of yeast telomerase depends on the importin mtr10. Mol Cell Biol 22(17):6046-55
Lewis LK, et al.  (2002) Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics 160(1):49-62
Livengood AJ, et al.  (2002) Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol 22(7):2366-74
Seto AG, et al.  (2002) A bulged stem tethers Est1p to telomerase RNA in budding yeast. Genes Dev 16(21):2800-12
Taggart AK, et al.  (2002) Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 297(5583):1023-6
Teixeira MT, et al.  (2002) Intracellular trafficking of yeast telomerase components. EMBO Rep 3(7):652-9
Chan SW, et al.  (2001) Altering telomere structure allows telomerase to act in yeast lacking ATM kinases. Curr Biol 11(16):1240-50
Chen Q, et al.  (2001) Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events. Mol Cell Biol 21(5):1819-27
Dez C, et al.  (2001) Stable expression in yeast of the mature form of human telomerase RNA depends on its association with the box H/ACA small nucleolar RNP proteins Cbf5p, Nhp2p and Nop10p. Nucleic Acids Res 29(3):598-603
Forstemann K and Lingner J  (2001) Molecular basis for telomere repeat divergence in budding yeast. Mol Cell Biol 21(21):7277-86
Peterson SE, et al.  (2001) The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku. Nat Genet 27(1):64-7
Grandin N, et al.  (2000) Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment. Mol Cell Biol 20(22):8397-408
Hughes TR, et al.  (2000) The Est3 protein is a subunit of yeast telomerase. Curr Biol 10(13):809-12
Niu H, et al.  (2000) Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex. Mol Cell Biol 20(18):6806-15
Prescott JC and Blackburn EH  (2000) Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres. Mol Cell Biol 20(8):2941-8
Evans SK and Lundblad V  (1999) Est1 and Cdc13 as comediators of telomerase access. Science 286(5437):117-20
Le S, et al.  (1999) RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics 152(1):143-52
Lue NF  (1999) Sequence-specific and conformation-dependent binding of yeast telomerase RNA to single-stranded telomeric DNA. Nucleic Acids Res 27(12):2560-7
Ritchie KB, et al.  (1999) Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. Mol Cell Biol 19(9):6065-75
Seto AG, et al.  (1999) Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle. Nature 401(6749):177-80
Henning KA, et al.  (1998) Humanizing the yeast telomerase template. Proc Natl Acad Sci U S A 95(10):5667-71
Lue NF and Xia J  (1998) Species-specific and sequence-specific recognition of the dG-rich strand of telomeres by yeast telomerase. Nucleic Acids Res 26(6):1495-502
Singer MS, et al.  (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32
Yamada M, et al.  (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem 273(50):33360-6
Cohn M and Blackburn EH  (1995) Telomerase in yeast. Science 269(5222):396-400