SPT14/YPL175W Literature Guide Help

Other names published for SPT14: CWH6, GPI3, YPL175W

SPT14 - Function/Process (16)

ReferenceOther Genes Addressed
Breinig F, et al.  (2004) Yeast Kre1p is GPI-anchored and involved in both cell wall assembly and architecture. Microbiology 150(Pt 10):3209-18
Kostova Z, et al.  (2003) Comparative importance in vivo of conserved glutamate residues in the EX7E motif retaining glycosyltransferase Gpi3p, the UDP-GlcNAc-binding subunit of the first enzyme in glycosylphosphatidylinositol assembly. Eur J Biochem 270(22):4507-14
Yan BC, et al.  (2001) Ynl038wp (Gpi15p) is the Saccharomyces cerevisiae homologue of human Pig-Hp and participates in the first step in glycosylphosphatidylinositol assembly. Yeast 18(15):1383-9
Cullen PJ, et al.  (2000) Defects in protein glycosylation cause SHO1-dependent activation of a STE12 signaling pathway in yeast. Genetics 155(3):1005-18
Kostova Z, et al.  (2000) Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis. Biochem J 350 Pt 3():815-22
Gaynor EC, et al.  (1999) MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast. Mol Biol Cell 10(3):627-48
Mazhari-Tabrizi R, et al.  (1999) Chromosomal promoter replacement in Saccharomyces cerevisiae: construction of conditional lethal strains for the cloning of glycosyltransferases from various organisms. Glycoconj J 16(11):673-9
Vossen JH, et al.  (1997) Restrictive glycosylphosphatidylinositol anchor synthesis in cwh6/gpi3 yeast cells causes aberrant biogenesis of cell wall proteins. J Bacteriol 179(7):2202-9
Inoue N, et al.  (1996) PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2. Biochem Biophys Res Commun 226(1):193-9
Leidich SD and Orlean P  (1996) Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis. J Biol Chem 271(44):27829-37
Leidich SD, et al.  (1995) Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene. J Biol Chem 270(22):13029-35
Schonbachler M, et al.  (1995) The yeast spt14 gene is homologous to the human PIG-A gene and is required for GPI anchor synthesis. EMBO J 14(8):1637-45
Vossen JH, et al.  (1995) Identification of SPT14/CWH6 as the yeast homologue of hPIG-A, a gene involved in the biosynthesis of GPI anchors. Biochim Biophys Acta 1243(3):549-51
Kawagoe K, et al.  (1994) Molecular cloning of murine pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus. Genomics 23(3):566-74
Fassler JS, et al.  (1991) The Saccharomyces cerevisiae SPT14 gene is essential for normal expression of the yeast transposon, Ty, as well as for expression of the HIS4 gene and several genes in the mating pathway. Mol Gen Genet 230(1-2):310-20
Fassler JS and Winston F  (1988) Isolation and analysis of a novel class of suppressor of Ty insertion mutations in Saccharomyces cerevisiae. Genetics 118(2):203-12