MET4/YNL103W Literature Guide Help

Other names published for MET4: YNL103W

MET4 - Function/Process (37)

ReferenceOther Genes Addressed
Baudouin-Cornu P, et al.  (2012) Glutathione degradation is a key determinant of glutathione homeostasis. J Biol Chem 287(7):4552-61
McIsaac RS, et al.  (2012) Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway. Mol Biol Cell 23(15):2993-3007
Hickman MJ, et al.  (2011) Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast. Mol Biol Cell 22(21):4192-204
Siggers T, et al.  (2011) Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex. Mol Syst Biol 7():555
Ouni I, et al.  (2010) A transcriptional activator is part of an SCF ubiquitin ligase to control degradation of its cofactors. Mol Cell 40(6):954-64
Wu WS and Chen BS  (2009) Identifying Stress Transcription Factors Using Gene Expression and TF-Gene Association Data. Bioinform Biol Insights 1():137-45
Su NY, et al.  (2008) A Dominant Suppressor Mutation of the met30 Cell Cycle Defect Suggests Regulation of the Saccharomyces cerevisiae Met4-Cbf1 Transcription Complex by Met32. J Biol Chem 283(17):11615-24
Ward LD and Bussemaker HJ  (2008) Predicting functional transcription factor binding through alignment-free and affinity-based analysis of orthologous promoter sequences. Bioinformatics 24(13):i165-71
Yuan S and Li KC  (2007) Context-dependent clustering for dynamic cellular state modeling of microarray gene expression. Bioinformatics 23(22):3039-47
Flick K, et al.  (2006) A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome. Nat Cell Biol 8(5):509-15
Leroy C, et al.  (2006) Independent recruitment of mediator and SAGA by the activator Met4. Mol Cell Biol 26(8):3149-63
Menant A, et al.  (2006) Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor. J Biol Chem 281(17):11744-54
Titz B, et al.  (2006) Transcriptional activators in yeast. Nucleic Acids Res 34(3):955-67
Barbey R, et al.  (2005) Inducible dissociation of SCF(Met30) ubiquitin ligase mediates a rapid transcriptional response to cadmium. EMBO J 24(3):521-32
Yen JL, et al.  (2005) The yeast ubiquitin ligase SCFMet30 regulates heavy metal response. Mol Biol Cell 16(4):1872-82
Aranda A and del Olmo ML  (2004) Exposure of Saccharomyces cerevisiae to acetaldehyde induces sulfur amino acid metabolism and polyamine transporter genes, which depend on Met4p and Haa1p transcription factors, respectively. Appl Environ Microbiol 70(4):1913-22
Brunson LE, et al.  (2004) The amino-terminal portion of the F-box protein Met30p mediates its nuclear import and assimilation into an SCF complex. J Biol Chem 279(8):6674-82
Flick K, et al.  (2004) Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain. Nat Cell Biol 6(7):634-41
Hochstrasser M  (2004) Ubiquitin signalling: what's in a chain? Nat Cell Biol 6(7):571-2
Freiman RN and Tjian R  (2003) Regulating the regulators: lysine modifications make their mark. Cell 112(1):11-7
Wheeler GL, et al.  (2003) Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors. J Biol Chem 278(50):49920-8
Fauchon M, et al.  (2002) Sulfur sparing in the yeast proteome in response to sulfur demand. Mol Cell 9(4):713-23
Kuras L, et al.  (2002) Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment. Mol Cell 10(1):69-80
Wheeler GL, et al.  (2002) Glutathione regulates the expression of gamma-glutamylcysteine synthetase via the Met4 transcription factor. Mol Microbiol 46(2):545-56
Dormer UH, et al.  (2000) Cadmium-inducible expression of the yeast GSH1 gene requires a functional sulfur-amino acid regulatory network. J Biol Chem 275(42):32611-6
Kaiser P, et al.  (2000) Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4. Cell 102(3):303-14
Moler EJ, et al.  (2000) Integrating naive Bayes models and external knowledge to examine copper and iron homeostasis in S. cerevisiae. Physiol Genomics 4(2):127-135
Rouillon A, et al.  (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94
Miyake T, et al.  (1999) Role of the sulphate assimilation pathway in utilization of glutathione as a sulphur source by Saccharomyces cerevisiae. Yeast 15(14):1449-57
Blaiseau PL and Thomas D  (1998) Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA. EMBO J 17(21):6327-36