TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Function/Process (90)

Results: 61 - 90 of 90 records
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ReferenceOther Genes Addressed
Jensen S, et al.  (1996) Analysis of functional domain organization in DNA topoisomerase II from humans and Saccharomyces cerevisiae. Mol Cell Biol 16(7):3866-77
Nitiss JL and Wang JC  (1996) Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA. Mol Pharmacol 50(5):1095-102
Roca J and Wang JC  (1996) The probabilities of supercoil removal and decatenation by yeast DNA topoisomerase II. Genes Cells 1(1):17-27
Rodriguez-Campos A  (1996) DNA knotting abolishes in vitro chromatin assembly. J Biol Chem 271(24):14150-5
Skladanowski A, et al.  (1996) Inhibition of DNA topoisomerase II by imidazoacridinones, new antineoplastic agents with strong activity against solid tumors. Mol Pharmacol 49(5):772-80
Elsea SH, et al.  (1995) A yeast type II topoisomerase selected for resistance to quinolones. Mutation of histidine 1012 to tyrosine confers resistance to nonintercalative drugs but hypersensitivity to ellipticine. J Biol Chem 270(4):1913-20
Froelich-Ammon SJ and Osheroff N  (1995) Topoisomerase poisons: harnessing the dark side of enzyme mechanism. J Biol Chem 270(37):21429-32
Froelich-Ammon SJ, et al.  (1995) Increased drug affinity as the mechanistic basis for drug hypersensitivity of a mutant type II topoisomerase. J Biol Chem 270(47):28018-21
Roca J  (1995) The mechanisms of DNA topoisomerases. Trends Biochem Sci 20(4):156-60
Vassetzky YS, et al.  (1995) DNA topoisomerase II mutations and resistance to anti-tumor drugs. Bioessays 17(9):767-74
Chen AY and Liu LF  (1994) Mechanisms of resistance to topoisomerase inhibitors. Cancer Treat Res 73():263-81
Dang Q, et al.  (1994) Phosphorylation of the C-terminal domain of yeast topoisomerase II by casein kinase II affects DNA-protein interaction. J Mol Biol 243(1):10-24
Liu YX, et al.  (1994) Yeast topoisomerase II mutants resistant to anti-topoisomerase agents: identification and characterization of new yeast topoisomerase II mutants selected for resistance to etoposide. Cancer Res 54(11):2943-51
Nitiss JL, et al.  (1994) Mutations in the gyrB domain of eukaryotic topoisomerase II can lead to partially dominant resistance to etoposide and amsacrine. Mol Pharmacol 46(4):773-7
Roca J, et al.  (1994) Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. Proc Natl Acad Sci U S A 91(5):1781-5
Shen LL and Fostel JM  (1994) DNA topoisomerase inhibitors as antifungal agents. Adv Pharmacol 29B():227-44
Vassetzky YS, et al.  (1994) Topoisomerase II forms multimers in vitro: effects of metals, beta-glycerophosphate, and phosphorylation of its C-terminal domain. Mol Cell Biol 14(10):6962-74
Cardenas ME and Gasser SM  (1993) Regulation of topoisomerase II by phosphorylation: a role for casein kinase II. J Cell Sci 104 ( Pt 2)():219-25
Wasserman RA, et al.  (1993) Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase II alpha in yeast. Cancer Res 53(15):3591-6
Adachi N, et al.  (1992) Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation. Nucleic Acids Res 20(20):5297-303
Bojanowski K, et al.  (1992) Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells. Proc Natl Acad Sci U S A 89(7):3025-9
Gartenberg MR and Wang JC  (1992) Positive supercoiling of DNA greatly diminishes mRNA synthesis in yeast. Proc Natl Acad Sci U S A 89(23):11461-5
Roca J and Wang JC  (1992) The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases. Cell 71(5):833-40
Chung IK and Muller MT  (1991) Aggregates of oligo(dG) bind and inhibit topoisomerase II activity and induce formation of large networks. J Biol Chem 266(15):9508-14
Pocklington MJ, et al.  (1990) The effect of novobiocin on yeast topoisomerase type II. Mol Gen Genet 220(2):256-60
Figgitt DP, et al.  (1989) Topoisomerase II: a potential target for novel antifungal agents. Biochem Biophys Res Commun 160(1):257-62
Christman MF, et al.  (1988) Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. Cell 55(3):413-25
Saavedra RA and Huberman JA  (1986) Both DNA topoisomerases I and II relax 2 micron plasmid DNA in living yeast cells. Cell 45(1):65-70
DiNardo S, et al.  (1984) DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication. Proc Natl Acad Sci U S A 81(9):2616-20
Goto T and Wang JC  (1982) Yeast DNA topoisomerase II. An ATP-dependent type II topoisomerase that catalyzes the catenation, decatenation, unknotting, and relaxation of double-stranded DNA rings. J Biol Chem 257(10):5866-72
Results: 61 - 90 of 90 records
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