TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Function/Process (90)

Results: 31 - 60 of 90 records
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ReferenceOther Genes Addressed
Mondal N, et al.  (2003) Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity. Nucleic Acids Res 31(17):5016-24
Bachant J, et al.  (2002) The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol Cell 9(6):1169-82
Bhalla N, et al.  (2002) Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior. Mol Biol Cell 13(2):632-45
Strumberg D, et al.  (2002) Importance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action. Antimicrob Agents Chemother 46(9):2735-46
Trigueros S and Roca J  (2002) A GyrB-GyrA fusion protein expressed in yeast cells is able to remove DNA supercoils but cannot substitute eukaryotic topoisomerase II. Genes Cells 7(3):249-57
Trigueros S and Roca J  (2002) Failure to relax negative supercoiling of DNA is a primary cause of mitotic hyper-recombination in topoisomerase-deficient yeast cells. J Biol Chem 277(40):37207-11
Baird CL, et al.  (2001) The ATPase reaction cycle of yeast DNA topoisomerase II. Slow rates of ATP resynthesis and P(i) release. J Biol Chem 276(30):27893-8
Byl JA, et al.  (2001) DNA topoisomerase II as the target for the anticancer drug TOP-53: mechanistic basis for drug action. Biochemistry 40(3):712-8
Nitiss JL, et al.  (2001) Overexpression of type I topoisomerases sensitizes yeast cells to DNA damage. J Biol Chem 276(28):26708-14
Roca J  (2001) Varying levels of positive and negative supercoiling differently affect the efficiency with which topoisomerase II catenates and decatenates DNA. J Mol Biol 305(3):441-50
Trigueros S and Roca J  (2001) Circular minichromosomes become highly recombinogenic in topoisomerase-deficient yeast cells. J Biol Chem 276(3):2243-8
Wang H, et al.  (2001) Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation. Biochemistry 40(11):3316-23
Morris SK, et al.  (2000) Steady-state and rapid kinetic analysis of topoisomerase II trapped as the closed-clamp intermediate by ICRF-193. J Biol Chem 275(4):2613-8
Baird CL, et al.  (1999) Topoisomerase II drives DNA transport by hydrolyzing one ATP. Proc Natl Acad Sci U S A 96(24):13685-90
Leroy D, et al.  (1999) Mutations in the C-terminal domain of topoisomerase II affect meiotic function and interaction with the casein kinase 2 beta subunit. Mol Cell Biochem 191(1-2):85-95
Morris SK and Lindsley JE  (1999) Yeast topoisomerase II is inhibited by etoposide after hydrolyzing the first ATP and before releasing the second ADP. J Biol Chem 274(43):30690-6
Morris SK, et al.  (1999) Kinetic and thermodynamic analysis of mutant type II DNA topoisomerases that cannot covalently cleave DNA. J Biol Chem 274(6):3446-52
Olland S and Wang JC  (1999) Catalysis of ATP hydrolysis by two NH(2)-terminal fragments of yeast DNA topoisomerase II. J Biol Chem 274(31):21688-94
Schultz MC  (1999) Chromatin assembly in yeast cell-free extracts. Methods 17(2):161-72
Liu Q and Wang JC  (1998) Identification of active site residues in the "GyrA" half of yeast DNA topoisomerase II. J Biol Chem 273(32):20252-60
Reid RJ, et al.  (1998) Yeast as a model organism for studying the actions of DNA topoisomerase-targeted drugs. Biochim Biophys Acta 1400(1-3):289-300
Sabourin M, et al.  (1998) A mutant yeast topoisomerase II (top2G437S) with differential sensitivity to anticancer drugs in the presence and absence of ATP. J Biol Chem 273(44):29086-92
Benedetti P, et al.  (1997) Study of yeast DNA topoisomerase II and its truncation derivatives by transmission electron microscopy. J Biol Chem 272(18):12132-7
Garinther WI and Schultz MC  (1997) Topoisomerase function during replication-independent chromatin assembly in yeast. Mol Cell Biol 17(7):3520-6
Rybenkov VV, et al.  (1997) Simplification of DNA topology below equilibrium values by type II topoisomerases. Science 277(5326):690-3
Shaw SY and Wang JC  (1997) Chirality of DNA trefoils: implications in intramolecular synapsis of distant DNA segments. Proc Natl Acad Sci U S A 94(5):1692-7
Tennyson RB and Lindsley JE  (1997) Type II DNA topoisomerase from Saccharomyces cerevisiae is a stable dimer. Biochemistry 36(20):6107-14
Berger JM, et al.  (1996) Structure and mechanism of DNA topoisomerase II. Nature 379(6562):225-32
Cavalli G, et al.  (1996) Inactivation of topoisomerases affects transcription-dependent chromatin transitions in rDNA but not in a gene transcribed by RNA polymerase II. EMBO J 15(3):590-7
Hung F, et al.  (1996) Characterization of topoisomerase II-DNA interaction and identification of a DNA-binding domain by ultraviolet laser crosslinking. FEBS Lett 380(1-2):127-32
Results: 31 - 60 of 90 records
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