TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Function/Process (90)

Results: 1 - 30 of 90 records
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ReferenceOther Genes Addressed
Garcia-Rubio ML and Aguilera A  (2012) Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes. Nucleic Acids Res 40(3):1050-64
Hashash N, et al.  (2012) Topoisomerase II- and Condensin-Dependent Breakage of MEC1(ATR)-Sensitive Fragile Sites Occurs Independently of Spindle Tension, Anaphase, or Cytokinesis. PLoS Genet 8(10):e1002978
Hasinoff BB, et al.  (2012) The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II. Biochem Pharmacol 84(12):1617-26
Joshi RS, et al.  (2012) Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res 40(16):7907-15
Schmidt BH, et al.  (2012) Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat Struct Mol Biol 19(11):1147-54
Baxter J, et al.  (2011) Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes. Science 331(6022):1328-32
French SL, et al.  (2011) Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes. Mol Cell Biol 31(3):482-94
Sperling AS, et al.  (2011) Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proc Natl Acad Sci U S A 108(31):12693-8
El Hage A, et al.  (2010) Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev 24(14):1546-58
Fachinetti D, et al.  (2010) Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements. Mol Cell 39(4):595-605
Bermejo R, et al.  (2009) Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell 138(5):870-84
D'Ambrosio C, et al.  (2008) Condensin-Dependent rDNA Decatenation Introduces a Temporal Pattern to Chromosome Segregation. Curr Biol 18(14):1084-9
Rogojina AT and Nitiss JL  (2008) Isolation and Characterization of mAMSA-hypersensitive Mutants: CYTOTOXICITY OF Top2 COVALENT COMPLEXES CONTAINING DNA SINGLE STRAND BREAKS. J Biol Chem 283(43):29239-50
Takahashi Y, et al.  (2008) Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genet 4(10):e1000215
Warsi TH, et al.  (2008) DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint. Mol Biol Cell 19(10):4421-33
Wilstermann AM, et al.  (2007) Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme. Biochemistry 46(28):8217-25
Andrews CA, et al.  (2006) A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin. Genes Dev 20(9):1162-74
Barker CR, et al.  (2006) The identification and characterisation of a functional interaction between arginyl-tRNA-protein transferase and topoisomerase II. Biochem Biophys Res Commun 342(2):596-604
Cline SD and Hanawalt PC  (2006) Topoisomerase deficiencies subtly enhance global genomic repair of ultraviolet-induced DNA damage in Saccharomyces cerevisiae. DNA Repair (Amst) 5(5):611-7
Malik M, et al.  (2006) Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage. Mol Cancer Ther 5(6):1405-14
Mouchel NA and Jenkins JR  (2006) The identification of a functional interaction between PKC and topoisomerase II. FEBS Lett 580(1):51-7
Mueller-Planitz F and Herschlag D  (2006) Interdomain communication in DNA topoisomerase II. DNA binding and enzyme activation. J Biol Chem 281(33):23395-404
Salceda J, et al.  (2006) Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA. EMBO J 25(11):2575-83
de Mejia EG, et al.  (2006) Catalytic inhibition of human DNA topoisomerase by phenolic compounds in Ardisia compressa extracts and their effect on human colon cancer cells. Food Chem Toxicol 44(8):1191-203
Aguilar C, et al.  (2005) Topoisomerase II suppresses the temperature sensitivity of Saccharomyces cerevisiae pds5 mutants, but not the defect in sister chromatid cohesion. Cell Cycle 4(9):1294-304
Hellauer K, et al.  (2005) Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiae. Mol Pharmacol 68(5):1365-75
Hossain MS, et al.  (2004) DNA topoisomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast. Genes Cells 9(10):905-17
Roca J  (2004) The path of the DNA along the dimer interface of topoisomerase II. J Biol Chem 279(24):25783-8
Sullivan M, et al.  (2004) Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase. Cell 117(4):471-82
Trigueros S, et al.  (2004) Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology. J Mol Biol 335(3):723-31
Results: 1 - 30 of 90 records
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