ERG6/YML008C Literature Guide Help

Other names published for ERG6: ISE1, LIS1, SED6, VID1, sterol 24-C-methyltransferase, YML008C

ERG6 - Function/Process (50)

ReferenceOther Genes Addressed
Wlodarski T, et al.  (2011) Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome. PLoS One 6(8):e23168
Rossignol T, et al.  (2009) The proteome of a wine yeast strain during fermentation, correlation with the transcriptome. J Appl Microbiol 107(1):47-55
Zhang Z, et al.  (2009) [Regulation role of sterol C-24 methyltransferase and sterol C-8 isomerase in the ergosterol biosynthesis of Saccharomyces cerevisiae] Wei Sheng Wu Xue Bao 49(8):1063-8
Ganapathy K, et al.  (2008) Molecular probing of the Saccharomyces cerevisiae sterol 24-C methyltransferase reveals multiple amino acid residues involved with C(2)-transfer activity. Biochim Biophys Acta 1781(6-7):344-51
Jayasimha P and Nes WD  (2008) Photoaffinity Labeling and Mutational Analysis of 24-C-Sterol Methyltransferase Defines the AdoMet Binding Site. Lipids 43(8):681-93
Nes WD, et al.  (2008) Yeast sterol C24-methyltransferase: role of highly conserved tyrosine-81 in catalytic competence studied by site-directed mutagenesis and thermodynamic analysis. Arch Biochem Biophys 477(2):313-23
Grossmann G, et al.  (2006) Lipid raft-based membrane compartmentation of a plant transport protein expressed in Saccharomyces cerevisiae. Eukaryot Cell 5(6):945-53
Shobayashi M, et al.  (2006) A new method for isolation of S-adenosylmethionine (SAM)-accumulating yeast. Appl Microbiol Biotechnol 69(6):704-10
Proszynski TJ, et al.  (2005) A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. Proc Natl Acad Sci U S A 102(50):17981-6
Branco MR, et al.  (2004) Decrease of H2O2 plasma membrane permeability during adaptation to H2O2 in Saccharomyces cerevisiae. J Biol Chem 279(8):6501-6
Markovich S, et al.  (2004) Genomic approach to identification of mutations affecting caspofungin susceptibility in Saccharomyces cerevisiae. Antimicrob Agents Chemother 48(10):3871-6
Mo C, et al.  (2004) The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). Biochim Biophys Acta 1686(1-2):30-6
Nes WD, et al.  (2004) Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis. Biochemistry 43(2):569-76
Pourshafie M, et al.  (2004) Cloning of S-adenosyl-L-methionine:C-24-Delta-sterol-methyltransferase (ERG6) from Leishmania donovani and characterization of mRNAs in wild-type and amphotericin B-Resistant promastigotes. Antimicrob Agents Chemother 48(7):2409-14
Tedrick K, et al.  (2004) Enhanced membrane fusion in sterol-enriched vacuoles bypasses the Vrp1p requirement. Mol Biol Cell 15(10):4609-21
Anderson JB, et al.  (2003) Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Genetics 163(4):1287-98
Clark DD and Peterson BR  (2003) Analysis of protein tyrosine kinase inhibitors in recombinant yeast lacking the ERG6 gene. Chembiochem 4(1):101-7
Gupta SS, et al.  (2003) Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis. J Biol Chem 278(31):28831-9
Umebayashi K and Nakano A  (2003) Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane. J Cell Biol 161(6):1117-31
Valdez-Taubas J and Pelham HR  (2003) Slow diffusion of proteins in the yeast plasma membrane allows polarity to be maintained by endocytic cycling. Curr Biol 13(18):1636-40
Bagnat M and Simons K  (2002) Cell surface polarization during yeast mating. Proc Natl Acad Sci U S A 99(22):14183-8
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Eisenkolb M, et al.  (2002) A specific structural requirement for ergosterol in long-chain fatty acid synthesis mutants important for maintaining raft domains in yeast. Mol Biol Cell 13(12):4414-28
Emter R, et al.  (2002) ERG6 and PDR5 regulate small lipophilic drug accumulation in yeast cells via distinct mechanisms. FEBS Lett 521(1-3):57-61
Hongay C, et al.  (2002) Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae. EMBO J 21(15):4114-24
Nes WD, et al.  (2002) Active site mapping and substrate channeling in the sterol methyltransferase pathway. J Biol Chem 277(45):42549-56
Plowright AT, et al.  (2002) Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity. Chem Biol 9(5):607-18
Kato M and Wickner W  (2001) Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion. EMBO J 20(15):4035-40
Pichler H, et al.  (2001) A subfraction of the yeast endoplasmic reticulum associates with the plasma membrane and has a high capacity to synthesize lipids. Eur J Biochem 268(8):2351-61
Sitcheran R, et al.  (2000) A genetic analysis of glucocorticoid receptor signaling. Identification and characterization of ligand-effect modulators in Saccharomyces cerevisiae. Genetics 156(3):963-72