Other names published for MEC3: PIP3, PSO9, YLR288C
MEC3 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Other Topics
- Additional Information
MEC3 - Function/Process (51)
| Reference | Other Genes Addressed |
|---|---|
| Collura A, et al. (2012) Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11(3):294-303 | |
| Schmidt KH, et al. (2010) Formation of complex and unstable chromosomal translocations in yeast.LID - e12007 [pii] PLoS One 5(8) | |
| Navadgi-Patil VM and Burgers PM (2008) Yeast DNA Replication Protein Dpb11 Activates the Mec1/ATR Checkpoint Kinase. J Biol Chem 283(51):35853-9 | |
| Razidlo DF and Lahue RS (2008) Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. DNA Repair (Amst) 7(4):633-40 | |
| Grandin N and Charbonneau M (2007) Control of the yeast telomeric senescence survival pathways of recombination by the Mec1 and Mec3 DNA damage sensors and RPA. Nucleic Acids Res 35(3):822-38 | |
| Ogiwara H, et al. (2006) Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair. Nucleic Acids Res 34(11):3389-98 | |
| Huang ME and Kolodner RD (2005) A biological network in Saccharomyces cerevisiae prevents the deleterious effects of endogenous oxidative DNA damage. Mol Cell 17(5):709-20 | |
| Majka J and Burgers PM (2005) Function of Rad17/Mec3/Ddc1 and its partial complexes in the DNA damage checkpoint. DNA Repair (Amst) 4(10):1189-94 | |
| Sabbioneda S, et al. (2005) The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae. J Biol Chem 280(46):38657-65 | |
| Baroni E, et al. (2004) The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol Cell Biol 24(10):4151-65 | |
| Jia X, et al. (2004) Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants. Genetics 166(2):753-64 | |
| Lin J, et al. (2004) Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response. Mol Biol Cell 15(4):1623-34 | |
| Brendel M, et al. (2003) Role of PSO genes in repair of DNA damage of Saccharomyces cerevisiae. Mutat Res 544(2-3):179-93 | |
| Giannattasio M, et al. (2003) Correlation between checkpoint activation and in vivo assembly of the yeast checkpoint complex Rad17-Mec3-Ddc1. J Biol Chem 278(25):22303-8 | |
| King WR, et al. (2003) Ionizing irradiation effects on S-phase in checkpoint mutants of the yeast Saccharomyces cerevisiae. Curr Genet 42(6):313-21 | |
| Majka J and Burgers PM (2003) Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc Natl Acad Sci U S A 100(5):2249-54 | |
| Mieczkowski PA, et al. (2003) Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae. Proc Natl Acad Sci U S A 100(19):10854-9 | |
| Enomoto S, et al. (2002) MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae. Mol Biol Cell 13(8):2626-38 | |
| Giannattasio M, et al. (2002) A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Proc Natl Acad Sci U S A 99(20):12997-3002 | |
| Maringele L and Lydall D (2002) EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev 16(15):1919-33 | |
| Venclovas C, et al. (2002) Molecular modeling-based analysis of interactions in the RFC-dependent clamp-loading process. Protein Sci 11(10):2403-16 | |
| Wang H and Elledge SJ (2002) Genetic and physical interactions between DPB11 and DDC1 in the yeast DNA damage response pathway. Genetics 160(4):1295-304 | |
| Grandin N, et al. (2001) Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination. EMBO J 20(21):6127-39 | |
| Klein HL (2001) Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae. Genetics 157(2):557-65 | |
| Melo JA, et al. (2001) Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev 15(21):2809-21 | |
| Myung K, et al. (2001) Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 104(3):397-408 | |
| Schramke V, et al. (2001) The set1Delta mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes. Genes Dev 15(14):1845-58 | |
| Zhang H, et al. (2001) Characterization of DNA damage-stimulated self-interaction of Saccharomyces cerevisiae checkpoint protein Rad17p. J Biol Chem 276(28):26715-23 | |
| Clarke DJ and Gimenez-Abian JF (2000) Checkpoints controlling mitosis. Bioessays 22(4):351-63 | |
| Foiani M, et al. (2000) DNA damage checkpoints and DNA replication controls in Saccharomyces cerevisiae. Mutat Res 451(1-2):187-96 | |




