GCN1/YGL195W Literature Guide Help

Other names published for GCN1: NDR1, AAS103, YGL195W

GCN1 - Function/Process (13)

ReferenceOther Genes Addressed
Visweswaraiah J, et al.  (2012) Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation. J Biol Chem 287(45):37757-68
Steffensen L and Pedersen PA  (2006) Heterologous expression of membrane and soluble proteins derepresses GCN4 mRNA translation in the yeast Saccharomyces cerevisiae. Eukaryot Cell 5(2):248-61
Sattlegger E and Hinnebusch AG  (2005) Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation. J Biol Chem 280(16):16514-21
Goossens A, et al.  (2001) The protein kinase Gcn2p mediates sodium toxicity in yeast. J Biol Chem 276(33):30753-60
Kubota H, et al.  (2001) Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2. J Biol Chem 276(20):17591-6
Garcia-Barrio M, et al.  (2000) Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation. EMBO J 19(8):1887-99
Kubota H, et al.  (2000) GI domain-mediated association of the eukaryotic initiation factor 2alpha kinase GCN2 with its activator GCN1 is required for general amino acid control in budding yeast. J Biol Chem 275(27):20243-6
Marton MJ, et al.  (1997) Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2. Mol Cell Biol 17(8):4474-89
Vazquez de Aldana CR, et al.  (1995) GCN20, a novel ATP binding cassette protein, and GCN1 reside in a complex that mediates activation of the eIF-2 alpha kinase GCN2 in amino acid-starved cells. EMBO J 14(13):3184-99
Marton MJ, et al.  (1993) GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2. Mol Cell Biol 13(6):3541-56
Ramirez M, et al.  (1992) Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases. Mol Cell Biol 12(12):5801-15
Cigan AM, et al.  (1991) Complex formation by positive and negative translational regulators of GCN4. Mol Cell Biol 11(6):3217-28
Briza P, et al.  (1986) Dityrosine is a prominent component of the yeast ascospore wall. A proof of its structure. J Biol Chem 261(9):4288-94