Other names published for SAE2: COM1, YGL175C
SAE2 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
SAE2 - Function/Process (34)
| Reference | Other Genes Addressed |
|---|---|
| Matsuzaki K, et al. (2012) Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection. Genes Cells 17(6):473-93 | |
| Zhang Y, et al. (2012) Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell 48(2):254-65 | |
| Bonetti D, et al. (2010) The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends. PLoS One 5(11):e14142 | |
| Hamilton NK and Maizels N (2010) MRE11 Function in Response to Topoisomerase Poisons Is Independent of its Function in Double-Strand Break Repair in Saccharomyces cerevisiae. PLoS One 5(10):e15387 | |
| Manfrini N, et al. (2010) Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases. J Biol Chem 285(15):11628-37 | |
| Nicolette ML, et al. (2010) Mre11-Rad50-Xrs2 and Sae2 promote 5' strand resection of DNA double-strand breaks. Nat Struct Mol Biol 17(12):1478-85 | |
| Shim EY, et al. (2010) Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks. EMBO J 29(19):3370-80 | |
| Sundararajan R, et al. (2010) Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiae. Genetics 184(1):65-77 | |
| Bonetti D, et al. (2009) Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres. Mol Cell 35(1):70-81 | |
| Doksani Y, et al. (2009) Replicon dynamics, dormant origin firing, and terminal fork integrity after double-strand break formation. Cell 137(2):247-58 | |
| Enserink JM, et al. (2009) Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae. J Cell Biol 185(3):423-37 | |
| Cartagena-Lirola H, et al. (2008) Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. Mol Cell Biol 28(14):4480-93 | |
| Cote AG and Lewis SM (2008) Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae. Mol Cell 31(6):800-12 | |
| Huertas P, et al. (2008) CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature 455(7213):689-92 | |
| Lee K, et al. (2008) Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations. Nature 454(7203):543-6 | |
| Mimitou EP and Symington LS (2008) Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455(7214):770-4 | |
| Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 | |
| Lengsfeld BM, et al. (2007) Sae2 Is an Endonuclease that Processes Hairpin DNA Cooperatively with the Mre11/Rad50/Xrs2 Complex. Mol Cell 28(4):638-51 | |
| Clerici M, et al. (2006) The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling. EMBO Rep 7(2):212-8 | |
| Lui DY, et al. (2006) Analysis of close stable homolog juxtaposition during meiosis in mutants of Saccharomyces cerevisiae. Genetics 173(3):1207-22 | |
| Clerici M, et al. (2005) The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends. J Biol Chem 280(46):38631-8 | |
| Deng C, et al. (2005) Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae. Genetics 170(2):591-600 | |
| Baroni E, et al. (2004) The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol Cell Biol 24(10):4151-65 | |
| Lisby M, et al. (2004) Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins. Cell 118(6):699-713 | |
| Yu J, et al. (2004) Microhomology-dependent end joining and repair of transposon-induced DNA hairpins by host factors in Saccharomyces cerevisiae. Mol Cell Biol 24(3):1351-64 | |
| Fukuda T, et al. (2003) VDE-initiated intein homing in Saccharomyces cerevisiae proceeds in a meiotic recombination-like manner. Genes Cells 8(7):587-602 | |
| Viscardi V, et al. (2003) Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae. Mol Biol Cell 14(8):3126-43 | |
| Lobachev KS, et al. (2002) The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell 108(2):183-93 | |
| Neale MJ, et al. (2002) Wild-type levels of Spo11-induced DSBs are required for normal single-strand resection during meiosis. Mol Cell 9(4):835-46 | |
| Rattray AJ, et al. (2001) Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1. Genetics 158(1):109-22 |





