CDC34/YDR054C Literature Guide Help

Other names published for CDC34: DNA6, UBC3, SCF E2 ubiquitin-protein ligase catalytic subunit CDC34, YDR054C

CDC34 - Function/Process (72)

ReferenceOther Genes Addressed
Khong JH, et al.  (2012) "Reductional anaphase" in replication-defective cells is caused by ubiquitin-conjugating enzyme Cdc34-mediated deregulation of the spindle. Cell Cycle 11(15):2896-910
Cocklin R, et al.  (2011) New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1. Genetics 187(3):701-15
Lass A, et al.  (2011) The loop-less tmCdc34 E2 mutant defective in polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2. Cell Div 6(1):7
Tumusiime S, et al.  (2011) Differential regulation of transcription factors Stp1 and Stp2 in the Ssy1-Ptr3-Ssy5 amino acid sensing pathway. J Biol Chem 286(6):4620-31
Cappell SD, et al.  (2010) Systematic analysis of essential genes reveals important regulators of G protein signaling. Mol Cell 38(5):746-57
Garrenton LS, et al.  (2009) Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence. Mol Cell Biol 29(2):582-601
Kleiger G, et al.  (2009) Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates. Cell 139(5):957-68
Kleiger G, et al.  (2009) The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCFCdc4. J Biol Chem 284(52):36012-23
Aviram S, et al.  (2008) Autophosphorylation-induced degradation of the Pho85 cyclin Pcl5 is essential for response to amino acid limitation. Mol Cell Biol 28(22):6858-69
Zaidi IW, et al.  (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9(10):1034-40
Hwang GW  (2007) A Ubiquitin-proteasome System as a Factor that Determine the Sensitivity to Methylmercury. Yakugaku Zasshi 127(3):463-8
Hwang GW, et al.  (2007) Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met4. Biochem Biophys Res Commun 363(3):873-8
Ii T, et al.  (2007) The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity. Cell Cycle 6(22):2800-9
Sadowski M, et al.  (2007) Cdc34 C-terminal tail phosphorylation regulates Skp1/cullin/F-box (SCF)-mediated ubiquitination and cell cycle progression. Biochem J 405(3):569-81
Scaglione KM, et al.  (2007) SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo. Mol Cell Biol 27(16):5860-70
Hiraishi H, et al.  (2006) Enhancement of Stress Tolerance in Saccharomyces cerevisiae by Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes. Biosci Biotechnol Biochem 70(11):2762-5
Petroski MD, et al.  (2006) Evaluation of a diffusion-driven mechanism for substrate ubiquitination by the SCF-Cdc34 ubiquitin ligase complex. Mol Cell 24(4):523-34
Yu L, et al.  (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47
Altmann K and Westermann B  (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7
Arnason TG, et al.  (2005) Novel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiae. Eukaryot Cell 4(1):134-46
Gardner RG, et al.  (2005) Degradation-mediated protein quality control in the nucleus. Cell 120(6):803-15
Petroski MD and Deshaies RJ  (2005) Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34. Cell 123(6):1107-20
Purnapatre K, et al.  (2005) Glucose inhibits meiotic DNA replication through SCFGrr1p-dependent destruction of Ime2p kinase. Mol Cell Biol 25(1):440-50
Bao MZ, et al.  (2004) Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast. Cell 119(7):991-1000
Flick K, et al.  (2004) Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain. Nat Cell Biol 6(7):634-41
Kus BM, et al.  (2004) Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro. Proteins 54(3):455-67
Deffenbaugh AE, et al.  (2003) Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1. Cell 114(5):611-22
Ke PY, et al.  (2003) Degradation of human thymidine kinase is dependent on serine-13 phosphorylation: involvement of the SCF-mediated pathway. Biochem J 370(Pt 1):265-73
Petroski MD and Deshaies RJ  (2003) Context of multiubiquitin chain attachment influences the rate of Sic1 degradation. Mol Cell 11(6):1435-44
Singer T, et al.  (2003) Sit4 phosphatase is functionally linked to the ubiquitin-proteasome system. Genetics 164(4):1305-21