RAM1/YDL090C Literature Guide Help

Other names published for RAM1: DPR1, FUS8, SCG2, SGP2, STE16, protein farnesyltransferase, YDL090C

RAM1 - Function/Process (15)

ReferenceOther Genes Addressed
Labadie GR, et al.  (2007) Farnesyl Diphosphate Analogues with omega-Bioorthogonal Azide and Alkyne Functional Groups for Protein Farnesyl Transferase-Catalyzed Ligation Reactions. J Org Chem 72(24):9291-9297
Liu XH and Prestwich GD  (2004) Didehydrofarnesyl diphosphate: an intrinsically fluorescent inhibitor of protein farnesyltransferase. Bioorg Med Chem Lett 14(9):2137-40
Harris CM, et al.  (2002) Modulation of the zinc(II) center in protein farnesyltransferase by mutagenesis of the zinc(II) ligands. Biochemistry 41(33):10554-62
Schmidt WK, et al.  (1998) Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage. Proc Natl Acad Sci U S A 95(19):11175-80
Chen P, et al.  (1997) Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor. J Cell Biol 136(2):251-69
Dolence JM, et al.  (1997) Yeast protein farnesyltransferase. Site-directed mutagenesis of conserved residues in the beta-subunit. Biochemistry 36(30):9246-52
Mathis JR and Poulter CD  (1997) Yeast protein farnesyltransferase: a pre-steady-state kinetic analysis. Biochemistry 36(21):6367-76
Dolence JM and Poulter CD  (1995) A mechanism for posttranslational modifications of proteins by yeast protein farnesyltransferase. Proc Natl Acad Sci U S A 92(11):5008-11
Dolence JM, et al.  (1995) Yeast protein farnesyltransferase: steady-state kinetic studies of substrate binding. Biochemistry 34(51):16687-94
Farh L, et al.  (1995) Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway. Arch Biochem Biophys 318(1):113-21
Caplin BE, et al.  (1994) Substrate characterization of the Saccharomyces cerevisiae protein farnesyltransferase and type-I protein geranylgeranyltransferase. Biochim Biophys Acta 1205(1):39-48
Gomez R, et al.  (1993) Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart. Biochem J 289 ( Pt 1)():25-31
Trueblood CE, et al.  (1993) Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae. Mol Cell Biol 13(7):4260-75
He B, et al.  (1991) RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins. Proc Natl Acad Sci U S A 88(24):11373-7
Schafer WR, et al.  (1990) Enzymatic coupling of cholesterol intermediates to a mating pheromone precursor and to the ras protein. Science 249(4973):1133-9