QCR6/YFR033C Literature Guide Help

Other names published for QCR6: COR3, UCR6, ubiquinol--cytochrome-c reductase subunit 6, YFR033C

QCR6 - Function/Process (35)

ReferenceOther Genes Addressed
Rottenberg H, et al.  (2009) Membrane Potential Greatly Enhances Superoxide Generation by the Cytochrome bc1 Complex Reconstituted into Phospholipid Vesicles. J Biol Chem 284(29):19203-10
Wenz T, et al.  (2009) Role of phospholipids in respiratory cytochrome bc(1) complex catalysis and supercomplex formation. Biochim Biophys Acta 1787(6):609-16
Ulanovskaya OA, et al.  (2008) Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Nat Chem Biol 4(7):418-24
Wenz T, et al.  (2007) Mutational analysis of cytochrome b at the ubiquinol oxidation site of yeast complex III. J Biol Chem 282(6):3977-88
Covian R and Trumpower BL  (2006) Regulatory interactions between ubiquinol oxidation and ubiquinone reduction sites in the dimeric cytochrome bc1 complex. J Biol Chem 281(41):30925-32
Ding MG, et al.  (2006) Investigating the Qn site of the cytochrome bc1 complex in Saccharomyces cerevisiae with mutants resistant to ilicicolin H, a novel Qn site inhibitor. J Biol Chem 281(47):36036-43
Hagerman RA, et al.  (2006) Ubiquinone accumulates in the mitochondria of yeast mutated in the ubiquinone binding protein, Qcr8p. Biochem Biophys Res Commun 344(1):241-5
Brasseur G, et al.  (2004) QO site deficiency can be compensated by extragenic mutations in the hinge region of the iron-sulfur protein in the bc1 complex of Saccharomyces cerevisiae. J Biol Chem 279(23):24203-11
Gutierrez-Cirlos EB, et al.  (2004) Inhibition of the yeast cytochrome bc1 complex by ilicicolin H, a novel inhibitor that acts at the Qn site of the bc1 complex. J Biol Chem 279(10):8708-14
Kessl JJ, et al.  (2003) Molecular basis for atovaquone binding to the cytochrome bc1 complex. J Biol Chem 278(33):31312-8
Muller FL, et al.  (2003) Architecture of the Qo site of the cytochrome bc1 complex probed by superoxide production. Biochemistry 42(21):6493-9
Palsdottir H, et al.  (2003) Structure of the yeast cytochrome bc1 complex with a hydroxyquinone anion Qo site inhibitor bound. J Biol Chem 278(33):31303-11
Pfeiffer K, et al.  (2003) Cardiolipin stabilizes respiratory chain supercomplexes. J Biol Chem 278(52):52873-80
Gutierrez-Cirlos EB and Trumpower BL  (2002) Inhibitory analogs of ubiquinol act anti-cooperatively on the Yeast cytochrome bc1 complex. Evidence for an alternating, half-of-the-sites mechanism of ubiquinol oxidation. J Biol Chem 277(2):1195-202
Gutierrez-Cirlos EB, et al.  (2002) Failure to insert the iron-sulfur cluster into the Rieske iron-sulfur protein impairs both center N and center P of the cytochrome bc1 complex. J Biol Chem 277(52):50703-9
Ghosh M, et al.  (2001) Substituting leucine for alanine-86 in the tether region of the iron-sulfur protein of the cytochrome bc1 complex affects the mobility of the [2Fe2S] domain. Biochemistry 40(2):327-35
Nett JH, et al.  (2000) Changes to the length of the flexible linker region of the Rieske protein impair the interaction of ubiquinol with the cytochrome bc1 complex. Eur J Biochem 267(18):5777-82
Obungu VH, et al.  (2000) Mutations in the tether region of the iron-sulfur protein affect the activity and assembly of the cytochrome bc(1) complex of yeast mitochondria. Biochim Biophys Acta 1457(1-2):36-44
DeLabre ML, et al.  (1999) The cleaved presequence is not required for import of subunit 6 of the cytochrome bc1 complex into yeast mitochondria or assembly into the complex. FEBS Lett 449(2-3):201-5
Boumans H, et al.  (1998) The respiratory chain in yeast behaves as a single functional unit. J Biol Chem 273(9):4872-7
Dick FA, et al.  (1997) QSR1, an essential yeast gene with a genetic relationship to a subunit of the mitochondrial cytochrome bc1 complex, codes for a 60 S ribosomal subunit protein. J Biol Chem 272(20):13372-9
Braun HP  (1996) Identification of novel homologues of three low molecular weight subunits of the mitochondrial bc1 complex. Mol Biol Rep 23(2):71-7
Tron T, et al.  (1995) QSR1, an essential yeast gene with a genetic relationship to a subunit of the mitochondrial cytochrome bc1 complex, is homologous to a gene implicated in eukaryotic cell differentiation. J Biol Chem 270(17):9961-70
Brandt U, et al.  (1994) Isolation and characterization of QCR10, the nuclear gene encoding the 8.5-kDa subunit 10 of the Saccharomyces cerevisiae cytochrome bc1 complex. J Biol Chem 269(17):12947-53
Yang M and Trumpower BL  (1994) Deletion of QCR6, the gene encoding subunit six of the mitochondrial cytochrome bc1 complex, blocks maturation of cytochrome c1, and causes temperature-sensitive petite growth in Saccharomyces cerevisiae. J Biol Chem 269(2):1270-5
Nakai M, et al.  (1993) Acidic regions of cytochrome c1 are essential for ubiquinol-cytochrome c reductase activity in yeast cells lacking the acidic QCR6 protein. J Biochem 114(6):919-25
Schmitt ME and Trumpower BL  (1991) The petite phenotype resulting from a truncated copy of subunit 6 results from loss of assembly of the cytochrome bc1 complex and can be suppressed by overexpression of subunit 9. J Biol Chem 266(23):14958-63
Schmitt ME and Trumpower BL  (1990) Subunit 6 regulates half-of-the-sites reactivity of the dimeric cytochrome bc1 complex in Saccharomyces cerevisiae. J Biol Chem 265(28):17005-11
Schoppink PJ, et al.  (1989) The effect of deletion of the genes encoding the 40 kDa subunit II or the 17 kDa subunit VI on the steady-state kinetics of yeast ubiquinol-cytochrome-c oxidoreductase. Biochim Biophys Acta 974(2):192-201
Crivellone MD, et al.  (1988) Assembly of the mitochondrial membrane system. Analysis of structural mutants of the yeast coenzyme QH2-cytochrome c reductase complex. J Biol Chem 263(28):14323-33